نتایج جستجو برای: inflammatory genes
تعداد نتایج: 673211 فیلتر نتایج به سال:
Abstract Inflammatory Bowel Disease (IBD) is a chronic inflammatory disease that affects the epithelial lining of gastrointestinal tract. Recent single cell RNA-sequencing (scRNA-seq) studies suggested inflammation-associated fibroblasts (IAFs) play important roles in pathogenesis and drug resistance. To elucidate IAF’s role IBD, we isolated from patients with IBD profiled their responses to pa...
Age-related dysregulated inflammation plays an essential role as a major risk factor underlying the pathophysiological aging process. To better understand how inflammatory processes are related to aging at the molecular level, we sequenced the transcriptome of young and aged rat kidney using RNA-Seq to detect known genes, novel genes, and alternative splicing events that are differentially expr...
Acidic tissue microenvironment commonly exists in inflammatory diseases, tumors, ischemic organs, sickle cell disease, and many other pathological conditions due to hypoxia, glycolytic cell metabolism and deficient blood perfusion. However, the molecular mechanisms by which cells sense and respond to the acidic microenvironment are not well understood. GPR4 is a proton-sensing receptor expresse...
Changes in vitamin D serum levels have been associated with inflammatory diseases, such as inflammatory bowel disease (IBD), rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis (MS), atherosclerosis, or asthma. Genome- and transcriptome-wide studies indicate that vitamin D signaling modulates many inflammatory responses on several levels. This includes (i) the regulation of t...
hemophagocytic lymphohistiocytosis (hlh) is an aggressive and potentially life-threatening disease and has to be considered in the differential diagnosis of many conditions. hlh comprises two different conditions that are difficult to differentiate; familial hemophagocytic lymphohistiocytosis (fhlh) or familial erythrophagocytic lymphohistiocytosis (fel), and secondary hemophagocytic syndromes ...
background pe5 is a member of the pe protein family whose precise function is yet to be understood. there are about 100 members of the pe family proteins in mycobacterium tuberculosis. these glycine- and alanine-rich proteins consist of proline-glutamate motifs at their n-termini and may be implicated in pathogenesis of the bacilli. objectives we aimed to clone and over-express the rv0285 codin...
anxiety comprises many clinical descriptions and phenotypes. a genetic predisposition to anxiety is undoubted; however, the nature and extent of that contribution is still unclear. extensive genetic studies of the serotonin (5-hydroxytryptamine, 5-ht) transporter (5-htt) gene have revealed how variation in gene expression can be correlated with anxiety phenotypes. complete genome-wide linkage s...
background :the cag pathogenicity island includes a number of genes, including cytotoxin-associated protein a (caga) and vacuolatingcytotoxin (vaca) genotypes, which are associated with bacterial virulence. although the role of caga and vaca in the virulence of helicobacter pylori (h. pylori) is well-established in epidemiological studies, the relationship between the caga and vaca genotypes in...
conclusions data reported here indicated that there is no specific genetic combination beyond the quantity of biofilm biomass in s. epidermidis. biofilm biomass seemed to be controlled by rnaiii expression level. further interest should be directed to biofilm dispersal since it seems that the key difference in biofilm biomass ability of s. epidermidis strains relates to factors regulating this ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید