BACKGROUND Following the emergence of the influenza A(H1N1)2009 virus, the French ministry of health decided to offer free vaccination against pandemic influenza to the entire French population. Groups of people were defined and prioritised for vaccination. METHODS We took a random sample of the population of mainland France and conducted a retrospective cross-sectional telephone survey to es...

A collection of Practice Guidelines published in AFP is available at http:// www.aafp.org/afp/ practguide. The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) has released its yearly recommendations for routine influenza vaccination in the 2015-2016 season. Updates this year include the antigenic composition of seasonal influenza vaccines availab...

Introduction: This study aimed to evaluate the clinical profile and outcomes of adult patients screened and diagnosed with H1N1 influenza infection at a tertiary care hospital in India. Materials and Methods: This retrospective  study was conducted on all adult patients suspected of H1N1 influenza admitted at a teaching hospital during the epidemic period of January-March 2015. Patients were sc...

Pandemic influenza A (H1N1) 2009 (pandemic H1N1) is spreading throughout the planet. It has become the dominant strain in the Southern Hemisphere, where the influenza season has now ended. Here, on the basis of reported case clusters in the United States, we estimated the household secondary attack rate for pandemic H1N1 to be 27.3% [95% confidence interval (CI) from 12.2% to 50.5%]. From a sch...

Influenza virus infection is a significant cause of morbidity and mortality worldwide. The surface antigens of influenza virus change over time blunting both naturally acquired and vaccine induced adaptive immune protection. Viral antigenic drift is a major contributing factor to both the spread and disease burden of influenza. The aim of this study was to develop better infection models using ...

background in 2009, a pandemic associated with a new type of influenza a virus (h1n1) affected many countries worldwide. after five years of silence, in 2015 we encountered another outbreak of h1n1 influenza a. objectives the present study aimed to study the epidemiological and clinical features of this disease in the cold and dry climate of qazvin province, iran in the last epidemic, during 20...

background emergence of a novel swine-origin influenza a (h1n1) pandemic since 2009 attracted the attention of scientists to characterize epidemiological features and clinical manifestations of this disease in comparison to seasonal flu in different parts of the world. objectives the goal of this investigation was to compare these features in confirmed cases of swine-origin influenza a (h1n1) a...

conclusions: prevalence rate of h1n1 infection in the study region was higher compared to other part of iran; but, close to the expected rate. the h1n1-associated mortality rate was lower than the reported rates in iran and other parts of the world. background: khuzestan and other parts of iran were involved with influenza a (h1n1) pandemic in 2009. objectives: the aim of this study was to desc...

BACKGROUND Live attenuated influenza H5N1 vaccines have been produced and evaluated in mice and ferrets that were never exposed to influenza A virus infection (Suguitan et al., Plos Medicine, e360:1541, 2006). However, the preexisting influenza heterosubtypic immunity on live attenuated H5N1 vaccine induced immune response has not been evaluated. METHODOLOGY AND PRINCIPAL FINDINGS Primary and...