Drugs for asthma and other chronic obstructive diseases of the lungs should be preferably delivered by the inhalation route to match therapeutic effects with low systemic exposure. Inhaled drugs are delivered to the lungs via different devices, mainly metered dose inhalers and dry powder inhalers, each characterized by specific inhaler technique and instructions for use. The patient-device inte...

BACKGROUND Prescribing inhalers without imparting adequate education regarding proper technique of their usage may result in suboptimal clinical improvement and wastage of medication. Training interventions using a standard check-list may help improve faulty techniques and enhance drug efficacy. METHODS Patients using metered dose inhaler (MDI) were included in the study. Inhaler technique wa...

BACKGROUND Poor adherence with prescribed asthma medication is a major barrier to positive treatment outcomes. This study was designed to determine the effect of a once-daily administration of mometasone furoate administered via a dry powder inhaler (MF-DPI) on treatment adherence compared with a twice-daily administration. METHODS This was a 12-week open-label study designed to mimic an actu...

BACKGROUND Physicians consider ease of use, satisfaction, and preferences when prescribing an inhaler device. These factors may impact appropriate usage and compliance. METHODS The objectives were to quantify the relative importance of inhaler attributes in patients currently using Combivent Respimat by eliciting preferences for performance and convenience attributes assessed by items in the ...

UNLABELLED Although community pharmacists have become more involved in the care of asthma patients, several studies have assessed pharmacists''ability to illustrate appropriately inhalation technique of different asthma devices. Many studies addressed inappropriate use of asthma devices by patients and pharmacists, in addition to its clinical, humanistic and economic burden. OBJECTIVE To eval...

Subanesthetic concentrations of desflurane and propofol suppress recall of emotionally charged information. alpha 4 subunit knockout mice are resistant to the amnes-tic effect of isoflurane. suppresses stress-enhanced fear learning in a rodent model of post-traumatic stress disorder. After receiving his B.S. from Michigan Agricultural College and then pursuing preliminary medical studies in Mic...

background: the most common treatment for asthma is transferring the drug into the lungs by inhaler devices. besides, correct use of inhaled medication is required for effectiveness of pharmacotherapy. thus, it is necessary to train the patients how to use metered dose inhaler (mdi). this study aimed to determine the effect of training about mdi usage with or without spacer on maximum expirator...

OBJECTIVE To evaluate the characteristics of users of inhalers and the prevalence of inhaler use among adolescents and adults with self-reported physician-diagnosed asthma, bronchitis, or emphysema. METHODS A population-based study conducted in the city of Pelotas, Brazil, involving 3,670 subjects ≥ 10 years of age, evaluated with a questionnaire. RESULTS Approximately 10% of the sample rep...

Smoking cessation is a key intervention for prevention of several lung diseases. The aim of the present study was to compare the effect of smoking cessation with nicotine replacement in a lung clinic in a low resource set-up suitable for implementation in other lung clinics. This was an open, randomized trial with 4 different nicotine replacement regimes combined with minimal behavioural suppor...

BACKGROUND Proper education regarding inhaler usage and optimal management of chronic obstructive pulmonary disease (COPD) is essential for effectively treating patients with COPD. This study was conducted to evaluate the effects of a comprehensive education program including inhaler training and COPD management. METHODS We enlisted 127 patients with COPD on an outpatient basis at 43 private ...