in an endeavor to find a novel series of antihyperglycemic agents, new benzimidazole and pyrimidine derivatives were successfully synthesized efficiently in high yield with high purity, starting from amino acids in the presence of phosphorus oxychloride (pocl3). the synthesized compounds were identified by 1h-nmr, 13c-nmr, ft-ir spectroscopic techniques and elemental analysis. all products were...

objectives: the purpose of this study was to compare the relationship between theory of mind and inhibitory responses in normal children and adhd. methods: this study is descriptive study, a sample size of 25 patients adhd children and 30 normal children, who were randomly selected. research instruments are questionnaires theory of mind and computerized stroop test. results: the results showed ...

this work studies the biosurfactants production which enables the diesel biodegradation byusing mixed microbial consortia from polluted sites. it was carried out by culturing three microbial consortia(named as xa, xb and xc) obtained from polluted soils, and enriched in diesel as sole carbon source.batchexperiments were done to study the effects of three variables (temperature,hydrocarbon conce...

to prepare hemagglutination inhibition (hi) antigen the egg drop syndrome virus (edsv) was propagated in 10-day-old embryonated duck eggs. the virus antigen was inactivated with two methods including heating (65°c) and adding 0.5% formaldehyde by considering low destroying effect on hemagglutination (ha) and hi titers. the edsv hi titers of 310 sera and 100 yolks obtained from 23 chicken farms ...

Beta-1,3-glucanases are enzymes that hydrolyze beta-1,3-glucans, and they essential for the metabolism of seaweed, plants fungi. These also participate in digestion herbivore fungivore animals. Because importance these enzymes in insects, beta-1,3-glucanase inhibitors may be used development new control strategies against agricultural pests disease vectors. Beta-1,3-glucanase inhibito...

Cyclooxygenase-2 (COX-2) has a pivotal role in the pathogenesis of the lung cancer. It is known that COX-2 negatively regulates the activity of a number of tumor suppressors, including p53. Consequently, inhibition of COX-2 signaling is anticipated to be a promising approach to stabilize p53 functionality. In this regard, we investigated the effect of COX-2 signaling blockade on p53 and COX-2 e...

A bacteriological investigation performed on the biopsies of 1 30 patients with gastrointestinal disorders at the GI section of Imam Khomeini hospital concluded in the isolation of 100 cases of Helicobacler pylori. The antibacterial effects of bismuth salts alone and in synergy with tetracycline and metronidazole were evaluated on the basis of disc diffusion method on 5 randomly selected pu...