BACKGROUND To summarize our results of intensity-modulated radiation therapy (IMRT) for prostate adenocarcinoma after cryotherapy failure. MATERIALS AND METHODS Patients underwent IMRT with curative intent for biochemically recurrent prostate cancer after cryotherapy. Radiation was delivered to a minimum dose of 72 Gy (range, 72-81 Gy). Acute and late treatment-related gastrointestinal and ge...

OBJECTIVE We evaluated health-related quality of life (HRQOL) in patients with localized prostate cancer who underwent intensity-modulated radiation therapy (IMRT) or three-field conformal radiotherapy (3DCRT). METHODS A total of 97 patients underwent 3DCRT and 36 underwent IMRT for localized prostate cancer between 2002 and 2004. We measured the general and disease-specific HRQOL with the Me...

Cancer, which is the uncontrolled division of cells, a leading fatal disease in world with high mortality rates. It can be treated using several methods, including radiotherapy, involves ionizing radiation. Radiotherapy on basis source placement has two types, i.e. brachytherapy and external beam radiotherapy. External radiotherapy evolved from 2-D conventional therapy to 3-D Conformal (3D-CRT)...

Purpose: To quantify the incidental radiation dose delivered to axilla and internal mammary nodal (IMN) area by Conventional Tangential Radiation Therapy (CRT), 3 Dimensional Conformal Radiation Therapy (3DCRT) and Intensity Modulated Radiation Therapy (IMRT). Methods and Materials: We prospectively evaluated incidental radiation to axilla in twenty cases of breast cancer treated with adjuvant ...

PURPOSE Radiation therapy plays an essential role in the treatment of locally advanced lung cancer, but it inevitably leads to incidental and unnecessary dose to critical organs, including the lung, heart, and esophagus. Numerous radiation dose-volumetric parameters have been associated with increased risk of morbidity and mortality. The purpose of the present study is to quantify differences i...

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Malignant thymomas are rare epithelial neoplasms of the anterior superior mediastinum that are typically invasive in nature and have a higher risk of relapse that may ultimately lead to death. Here we report a case of an advanced malignant thymoma that was successfully treated with neoadjuvant chemotherapy followed by surgical resection and subsequently with advanced and novel radiation therapy...

We consider the beam orientation optimization (BOO) problem for total marrow irradiation (TMI) treatment planning using intensity modulated radiation therapy (IMRT). Currently, IMRT is not widely used in TMI treatment delivery; furthermore, the effect of using non-coplanar beam orientations is not known. We propose and implement several variations of a single neighborhood search algorithm that ...

To investigate the plan quality of tri-Co-60 intensity-modulated radiation therapy (IMRT) with magnetic-resonance image-guided radiation therapy compared with volumetric-modulated arc therapy (VMAT) for prostate cancer. Twenty patients with intermediate-risk prostate cancer, who received radical VMAT were selected. Additional tri-Co-60 IMRT plans were generated for each patient. Both primary an...

PURPOSE To investigate whether an overlap volume histogram (OVH)-driven planning application using an intensity-modulated radiation therapy (IMRT) database can guide and automate volumetric-modulated arc therapy (VMAT) planning for head-and-neck cancer. METHODS Based on comparable head-and-neck dosimetric results between planner-generated VMAT and IMRT plans, an inhouse developed, OVH-driven ...