background: cutaneous manifestations are commonly observed in the neonatal period. it is important to differentiate physiologic skin lesions from pathologic ones to avoid parents’ concerns. regarding this, the current study aimed to investigate the frequency and localization of salmon patch (sp) and mongolian spot (ms) in iranian newborns to assess the potential relationship between the neonata...

Efficient delineation of conservation areas is a great challenge in maintaining biodiversity. Kernel density estimators (KDEs) are a powerful tool in this perspective, but they have not been applied at the population level on patch-distributed organisms. This would be particularly worthy for species that need broad habitats beyond those where they can be sampled; such as terrestrial lands for p...

Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

ewe abortion and neonatal mortality are serious problems to sheep farmer. the objective of this paper was to report isolation of erysipelothrix rhusiopathiae from aborted fetuses in a flock in tehran, iran. abortion occurred in 10% of ewes in the flock. the fetuses were well developed and pinpoint, necrotic-like lesions were recorded on the placental cotyledons, whilst the inter -cotyledonary a...

BACKGROUND When growing in reciprocal patches in terms of availability of different resources, connected ramets of clonal plants will specialize to acquire and exchange locally abundant resources more efficiently. This has been termed division of labour. We asked whether division of labour can occur physiologically as well as morphologically and will increase with patch contrasts. METHODOLOGY...

BACKGROUND Foot pain drawings (manikins) are commonly used to describe foot pain location in self-report health surveys. Respondents shade the manikin where they experience pain. The manikin is then scored via a transparent overlay that divides the drawings into areas. In large population based studies they are often scored by multiple raters. A difference in how different raters score manikins...

We address the failure in scalability of large-scale parallel simulations that are based on (semi-)implicit time-stepping and hence on the solution of linear systems on thousands of processors. We develop a general algorithmic framework based on domain decomposition that removes the scalability limitations and leads to optimal allocation of available computational resources. It is a non-intrusi...

Water deficit significantly limits dryland rainfed fruit production, so increasing water conservation is crucial for improving fruit productivity in arid and semiarid areas. In this study, we tested two treatments in an apple orchard: 1) PC treatment comprising black plastic mulch (BPM) (in-row) with weed control (inter-row); 2) and PGC treatment comprising BPM (in-row) combined with a summer c...

Lys48-linked ubiquitin chains act as the main targeting signals for protein degradation by the proteasome. Here we report selective binding of AIRAPL, a protein that associates with the proteasome upon exposure to arsenite, to Lys48-linked tri-ubiquitin chains. AIRAPL comprises two ubiquitin-interacting motifs in tandem (tUIMs) that are linked through a flexible inter-UIM region. In the complex...

which generally have little or no vegetation, produce runoff; sink areas, located downslope of the source arIn many semiarid regions, runoff and erosion differ according to eas, receive and store the runoff and thereby become vegetation patch type. These differences, although hypothesized to fundamentally affect ecological processes, have been poorly quantienriched and relatively productive. Th...