background: interferons (ifns) are common therapeutics for several diseases such as viral hepatitis, multiple sclerosis and malignancy. a variety of autoimmune related side effects have been observed during ifn therapy. rare cases of myopathy, polymyositis or dermatomyositis have been reported during therapy with high doses of ifn^5. case presentation: in this report, we describe a case with se...

Recent studies have shown an association between single nucleotide polymorphisms (SNPs) in the interferon lambda-3 (IFNL3 or IL-28B) and IFNL4 genes and treatment response to hepatitis C virus genotype 1 (HCV-1) infection. The importance of these SNPs for HCV genotype 3 (HCV-3), and particularly HCV genotype 6 (HCV-6), remains to be elucidated. We analyzed a cohort of 225 Thai individuals with ...

Following our general approach to Lambda-doubling specificity in the capture of dipolar molecules by ions [M. Auzinsh et al., J. Chem. Phys. 128, 184304 (2008)], we calculate the rate coefficients for the title process in the temperature range 10(-4)<T<10(2) K. Three regimes considered are as follows: (i) nonadiabatic capture in the regime of high-field Stark effect with respect to the Lambda-d...

We study scale-free networks constructed via a cooperative Achlioptas growth process. Links between nodes are introduced in order to produce a scale-free graph with given exponent lambda for the degree distribution, but the choice of each new link depends on the mass of the clusters that this link will merge. Networks constructed via this biased procedure show a percolation transition which str...

We study the behavior of scale-free networks, having connectivity distribution P(k) approximately k(-lambda), close to the percolation threshold. We show that for networks with 3<lambda<4, known to undergo a transition at a finite threshold of dilution, the critical exponents are different than the expected mean-field values of regular percolation in infinite dimensions. Networks with 2<lambda<...

 Let $P(lambda)$ be an $n$-square complex matrix polynomial, and $1 leq k leq n$ be a positive integer. In this paper, some algebraic and geometrical properties of the $k$-numerical range of $P(lambda)$ are investigated. In particular, the relationship between the $k$-numerical range of $P(lambda)$ and the $k$-numerical range of its companion linearization is stated. Moreover, the $k$-numerical...

Monospecific antibodies directed against the chicken progesterone receptor (PR) form B were used to screen a randomly primed phage lambda gt11 cDNA expression library prepared from size-fractionated chicken oviduct mRNA. Two independent immunoreactive clones, lambda cPR1 and lambda cPR2, were isolated. Antibodies selected from anti-PR form B antiserum on matrices of lambda cPR1 and lambda cPR2 ...

Quercetin as one of the key plant secondary metabolite flavonol is ubiquitous in terrestrial plants. In this study, the decrease in sensitivity to lambda-cyhalothrin was observed in quercetin-fed Helicoverpa armigera larvae. In order to figure out the mechanisms underlying the decreased sensitivity of H. armigera larvae to lambda-cyhalothrin by quercetin induction, the changes in carboxylestera...

BACKGROUND Genetic variation near the interferon lambda 3 (IFNL3) is known to be associated with response to pegylated interferon (pegIFN) and ribavirin combination therapy in patients with chronic hepatitis C virus (HCV) infection which is often accompanied by hepatic steatosis. AIMS We examined whether this genetic variation is associated with host lipids and treatment response. METHODS A...