in current work a comprehensive mechanism based on intermediate radical termination theory is assumed for raft polymerization of styrene over cumyl dithiobenzoate as raft agent. rate constants for addition (ka) and fragmentation reactions (kf) are set to 6×106 and 5×104 respectively, which lead to an equilibrium constant value of k = ka/kf = 1.2 x 102. moment equations method was used to model ...

background: xmn-1 polymorphism of y g globin gene ( hbg2 ) is a prominent quantitative trait loci (qtl) in β-thalassemia intermediate (β-ti). in current study, we evaluated frequency of xmn-1 polymorphism and its association with β-globin gene ( hbb ) alleles and hb f level in β-ti patients in sistan and balouchestan province, south-east of iran. methods: 45 β-ti patients were enrolled. hbb gen...

In this work, three possible mechanisms, including mechanisms A and B associated with the stereoselective [2 + 2] cycloaddition product and mechanism C associated with the [2 + 2 + 2] cycloaddition product, have been investigated for N-heterocyclic carbenes (NHCs) catalyzed cycloadditions of ketenes with isothiocyanates by using density functional theory (DFT). Our calculated results suggest th...

The box H/ACA RNA-guided pseudouridine synthase is a complicated ribonucleoprotein enzyme that recruits substrate via both the guide RNA and the catalytic subunit Cbf5. Structural studies have revealed multiple conformations of the enzyme, but a quantitative description of the reaction pathway is still lacking. Using fluorescence correlation spectroscopy, we here measured the equilibrium dissoc...

As the majority of new products fail it is important to focus on the needs and preferences of the consumers in new product development. Consumers are increasingly recognised as important codevelopers of innovations, often developing new functions for technologies, solving unforeseen problems and demanding innovative solutions. The central research question of the paper is: How to understand con...

in a previous paper, the second author established that, given finite fields $f < e$ and certain subgroups $c leq e^times$, there is a galois connection between the intermediate field lattice ${l mid f leq l leq e}$ and $c$'s subgroup lattice. based on the galois connection, the paper then calculated the irreducible, complex character degrees of the semi-direct product $c rtimes {rm gal} (e/f)$...

nanocrystalline complex oxides have been synthesized by combination of sol–gel auto combustion and ultrasonic irradiation techniques using copper nitrate, zinc nitrate as metallic nitrates and glycine, urea and thiourea as fuels. sol-gel combustion (combination of the chemical sol–gel process and the combustion process) as a proper synthesized technique is used to synthesize zno/cuo nanocomposi...

Vaccinia topoisomerase forms a covalent protein-DNA intermediate at sites containing the sequence 5'-CCCTT. The T nucleotide is linked via a 3'-phosphodiester bond to Tyr-274 of the enzyme. Here, we report that the enzyme catalyzes hydrolysis of the covalent intermediate, resulting in formation of a 3'-phosphate-terminated DNA cleavage product. The hydrolysis reaction is pH-dependent (optimum p...

During the war several English and American laboratories participated in a study of the structure and synthesis of penicillin (1, 2). In this work it was noted that when the methyl ester of benzylpenicillin (I) (see Fig. 1) was treated with mercuric chloride in ether solution and the resulting mercury derivative (II) was decomposed with hydrogen sulfide, a neutral, amorphous product was obtaine...

In Chlamydomonas chloroplasts, atpB pre-mRNA matures through a two-step process. Initially, endonuclease cleavage occurs 8-10 nt downstream of the mature 3' end, which itself lies at the end of a stem-loop-forming inverted repeat (IR) sequence. This intermediate product is then trimmed by a 3' -->5' exonuclease activity. Although the initial endonucleolytic cleavage by definition generates two ...