PURPOSE To determine the safety of an approach to immunologically enhance local treatment of hepatocellular cancer (HCC) by combining nonlethal radiation, local regional therapy with intratumoral injection, and systemic administration of a potent Toll-like receptor (TLR) immune adjuvant. METHODS Patients with HCC not eligible for liver transplant or surgery were subject to: 1) 3 fractions of ...

The pandemic crisis in 2020 has significantly impacted the tourism sector. Besides, sector is a that great potential economy and an alternative to replacing extractive sector, such as coal mining. Furthermore, new concepts related smart are also starting emerge, which expected help accelerate economic recovery. Based on this, this study aims evaluate effects of tourism, both intra- inter-region...

BACKGROUND Phase contrast velocimetry cardiovascular magnetic resonance (PC-CMR) is a powerful and versatile tool allowing assessment of in vivo motion of the myocardium. However, PC-CMR is sensitive to motion related artifacts causing errors that are geometrically systematic, rendering regional analysis of myocardial function challenging. The objective of this study was to establish an optimiz...

This paper interprets regional economic sustainability in the context of the globalization of late-coming regions. Drawing upon the concept of strategic coupling from economic geography, this paper proposes two types of strategic coupling, captive and proactive coupling, for better understanding regional sustainability and resilience through the experiences of the Pearl River Delta in China. It...

As from 2001, the Southern African Development Community (SADC) has embarked on a course to deepen regional integration through restructuring. Under the new structure SADC has centralised the coordination of its activities to the Secretariat in Gaborone. The former Sector Coordinating Units have been merged into four directorates, one of which is the Food, Agriculture and Natural Resources (FAN...

this study is carried out to determine effective risk factors for early death and their causes in those who died due to intra cerebral hemorrhage within 30 days.materials and methods: from patients who have been admitted in neurologic ward of imam khomeini hospital in tabriz, we enrolled 100 patients with intra cerebral hemorrhage and the causes and risk factors effective in early death were ev...

The effects of coronary occlusion and of subsequent propranolol administration were examined in 18 conscious dogs. Overall left ventricular (LV) function was assessed by measurements of LV pressure and dP/dt, and regional myocardial function was assessed by measurements of segment length (SL), velocity of SL shortening and regional myocardial "work", i.e., pressure-length loops in normal, moder...

Malignant peritoneal mesothelioma (MPM) is a malignancy that arises from the mesothelial lining of the abdominal cavity and largely manifests as a diffuse process. There are two hallmark features of MPM. First, MPM may progress and present itself diversely among patients. While some patients may endure a quick tumor progression that is refractory to seemingly successful initial therapeutic cyto...

The current study aims to analyze the factors influencing ASEAN economic growth and integration. Specifically, variables of inter-regional trade, human resource development, corruption were investigated in six lower-middle-income countries from 1996 2019 through Driscoll Kraay’s, Newey West’s, Dumitrescu Hurlin’s as causal analysis. study’s results found that capital had an impact 0.248%, labor...

In this study, we analyze the effect of knowledge spillover on productivity in Indonesian manufacturing industry from 2010 to 2014 using inter-sectoral linkages and inter-regional linkages. For first time literature, apply an input-output table geographic distance between regions as weight matrix spatial econometric estimation measure spillover. We find that: (1) transactions intermediate goods...