OBJECTIVE To determine the prediction rate of success in trial of labour after one previous caesarean section. METHODS The cross-sectional study was conducted at the Department of Obstetrics and Gynaecology, Cantonment General Hospital, Rawalpindi, from January 1, 2012 to January 31, 2013, and comprised women with one previous Caesarean section and with single alive foetus at 37-41 weeks of g...

Minimizing extra uterine growth restriction is a major factor in improving developmental outcomes of premature infants. Total parenteral nutrition is a valuable tool to provide nutrition soon after birth as preterm infants take time to establish enteral intake. Optimal growth is essential for premature infants to assure overall development. TPN supplementation is not without side effects, but a...

Introduction The aim of this study was to compare vaginal dinoprostone and mechanical methods for induction labor (IOL) in pregnancies complicated by late fetal growth restriction. Material Multicenter, retrospective, cohort involving six referral centers Italy Spain. Inclusion criteria were restriction as defined Delphi consensus criteria. primary outcome the occurrence uterine tachysystole; s...

OBJECTIVE To reduce average induction delivery internal in patients with poor Bishop score without compromising fetomaternal outcome (in terms of birth weight, NICU admission, maternal complications and mode of delivery). STUDY DESIGN A descriptive study. PLACE AND DURATION OF STUDY Department of Obstetrics and Gynaecology, Pakistan Atomic Energy Commission (PAEC) General Hospital, Islamaba...

Several decades of research have demonstrated that significant contributions to risk of cardiovascular disease are made by adult lifestyle factors such as smoking, high consumption of saturated fats and salt, low levels of physical activity, and obesity. The more recent assertion that the risk of hypertension and coronary heart disease in adult life may be determined by an adverse environment b...

We postulate that repeated pregnancy loss, intrauterine growth restriction, and preeclampsia are caused by impaired elevation of uterine blood flow due to disturbed arteriogenesis of the uterine arcade. This hypothesis is based on the observation that pregnant human erythropoietin-overexpressing (plasma levels elevated 12-fold) mice (termed tg6 mice) suffering from excessive erythrocytosis gene...

Growth restriction impacts on offspring development and increases their risk of disease in adulthood which is exacerbated with "second hits." The aim of this study was to investigate if blood pressure, glucose tolerance, and skeletal muscle mitochondrial biogenesis were altered in 12-month-old male and female offspring with prenatal or postnatal growth restriction. Bilateral uterine vessel liga...

BACKGROUND Fetal color Doppler is important for evaluation of hypoxia in intrauterine growth restriction (IUGR) fetus. OBJECTIVE In this study we compare fetal and maternal color Doppler with blood gas analysis to detect fetal acidosis. MATERIALS AND METHODS In this cross-sectional study we evaluated 100 hospitalized patients with IUGR for comparison of color Doppler results with arterial b...

We investigated intrauterine growth restriction, endothelial function, and uterine artery blood flow characteristics in a transgenic preeclampsia rat model with an activated renin-angiotensin system. We compared preeclamptic Sprague-Dawley (SD-PE) rats with normal pregnant Sprague-Dawley and nonpregnant Sprague-Dawley rats. We used transabdominal ultrasound and found that SD-PE rat embryos deve...

BACKGROUND Epidemiological studies have revealed a relationship between early growth restriction and the subsequent development of insulin resistance and type 2 diabetes. Ligation of the uterine arteries in rats mimics uteroplacental insufficiency and serves as a model of intrauterine growth restriction (IUGR) and subsequent developmental programming of impaired glucose tolerance, hyperinsuline...