INTRODUCTION There is much controversy about the optimal application of tranexamic acid (TXA) in total knee arthroplasty (TKA). The purpose of this meta-analysis was to compare the efficacy of the intra-articular and intravenous regimens of TXA in TKA. MATERIAL AND METHODS A literature search of the PubMed, Embase and Cochrane Library databases was performed. Randomized controlled trials comp...

BACKGROUND: The role of adenosine and ATP in the regulation of hepatic arterial blood flow in the "buffer response" was studied in vitro and in a new in vivo model in the rabbit. The model achieves portal-systemic diversion by insertion of a silicone rubber prosthesis between the portal vein and inferior vena cava and avoids alterations in systemic haemodynamics. RESULTS: Hepatic arterial (HA) ...

Sinusoidal obstruction syndrome (SOS)/hepatic veno-occlusive disease (VOD) is a fatal complication after hematopoietic stem cell transplantation. We previously reported the usefulness of an ultrasonographical (US) scoring system, Hokkaido US-based system consisting ten parameters (HokUS-10): (1) hepatomegaly in left lobe and (2) right lobe, (3) dilatation main portal vein (PV), (4) hepatofugal ...

Abstract Modafinil has a strong and long-lasting awakening effect. Short-term use can improve cognitive work efficiency. Therefore, it been known to be abused by students parents as “smart drug.” It is in the first category of psychotropic drugs strictly controlled. To detect modafinil rat plasma study differences pharmacokinetics between oral sublingual administration rats, an ultra-high perfo...

A 62-year-old man with progressive swelling on his left thigh and leg was referred to the Division of Vascular Surgery. Anticoagulation therapy did not prevent or improve the symptoms of chronic deep vein thrombosis (DVT) from his left external iliac vein to posterior tibial vein. He had no trauma history nor any accidents. He underwent femoral endovenectomy, thrombectomy and stent insertion in...

BACKGROUND Knowledge of the variant terminations of the portal vein is important in surgical and interventional radiological procedures of the liver. Their pattern and frequency are important in planning surgery to minimize complications. They differ between populations, but data from Africa is unavailable. AIM To investigate the variant termination of the main portal vein. MATERIALS AND ME...