The aim of this work is to describe our experience with an alternate surgical technique utilized in incomplete Strasberg E bile duct injuries, refractory to percutaneous and endoscopic dilation. These incomplete bile duct injuries have partial patency and no loss of continuity; and, should be considered as complex lesions in most cases. Stepup approach should be regarded. The surgical technique...

Bile acid accumulation in liver with cholangiolar neoplastic lesions may occur before cholestasis is clinically detected. Whether this favors intrahepatic cholangiocarcinoma development has been investigated in this study. The E. coli RecA gene promoter was cloned upstream from Luc2 to detect in vitro direct genotoxic ability by activation of SOS genes. This assay demonstrated that bile acids w...

UNLABELLED Bile acid accumulation in liver with cholangiolar neoplastic lesions may occur before cholestasis is clinically detected. Whether this favors intrahepatic cholangiocarcinoma development has been investigated in this study. The E. coli RecA gene promoter was cloned upstream from Luc2 to detect in vitro direct genotoxic ability by activation of SOS genes. This assay demonstrated that b...

BACKGROUND/AIMS Bile leakage is an uncommon but serious complication of cholecystectomy. The aim of this study is to evaluate the efficacy of the endoscopic management of bile leakage after cholecystectomy. METHODS A total of 32 patients who underwent endoscopic retrograde cholangiopancreatography (ERCP), because of bile leakage after cholecystectomy, from January 2000 to December 2012 were r...

Omega (ω)-3 polyunsaturated fatty acids appear to be effective in preventing and treating parenteral nutrition-associated liver disease, and several mechanisms were proposed for this observation. An 8-week-old male infant with cholestasis and acholic stool was diagnosed non-syndromic intrahepatic interlobular bile duct paucity by open-wedge liver biopsy. Initially he was treated with usual supp...

BACKGROUND There have been few prospective studies regarding the investigation of biliary strictures, principally because of rapid technological change. The present study was designed to determine the sensitivity of various imaging studies for the detection of biliary strictures. Serum biochemistry and imaging studies were evaluated for their role in distinguishing benign from malignant strictu...

We present a rare case of functional stenosis of the jejunal loop following left hepatectomy and hepaticojejunostomy long after pylorus-preserving pancreaticoduodenectomy (PPPD), which was successfully managed by balloon dilation. A 70-year-old Korean man had undergone PPPD 6 years before due to 1.8 cm-sized distal bile duct cancer. Sudden onset of obstructive jaundice led to diagnosis of recur...

PURPOSE Bile duct dilatation is a relatively common sonographic finding; nevertheless, its clinical significance in children is controversial because little research has been done in the area. Therefore, we investigated the natural course and clinical significance of biliary duct dilatation in children. METHODS We performed a retrospective study of 181 children (range, 1-day-old to 17-year-ol...

Three groups of newborn hamsters received a single s.c. injection of 0.2, 0.4, and 0.6 rug cycasin/g body weight within 24 hr after birth. Two groups of adult hamsters each received one dose of 0.1 or 0.15 rug cycasin/g body weight by stomach tube. Another three groups of adult hamsters received two to four doses of 0.1 rug cycasin/g body weight by stomach tube at intervals of 1 month. There wa...

This report describes antegrade electronic hydraulic lithotripsy (Lithotron EL 27; Walz Elektronik, Rohrdorf, Germany) using a digital peroral cholangioscope (SpyGlass DS System; Boston Scientific, Marlborough, Massachusetts, USA) [1, 2] through an endoscopic ultrasound (EUS)-guided hepaticojejunostomy route for common bile duct (CBD) stones (▶Video1). A 77-year-old man, who underwent total gas...