AIMS The EUTrigTreat clinical study has been designed as a prospective multicentre observational study and aims to (i) risk stratify patients with an implantable cardioverter defibrillator (ICD) for mortality and shock risk using multiple novel and established risk markers, (ii) explore a link between repolarization biomarkers and genetics of ion (Ca(2+), Na(+), K(+)) metabolism, (iii) compare ...

Background. Thrombolysis has altered treatment of acute myocardial infarction (AMI). Therefore, reevaluation of predictors of outcome and treatment strategies is appropriate. Methods and Results. Clinical variables collected prospectively for the 3,339 patients of the Thrombolysis in Myocardial Infarction II study were analyzed retrospectively to identify predictors of clinical events at 42 day...

Background. Thrombolysis has altered treatment of acute myocardial infarction (AMI). Therefore, reevaluation of predictors of outcome and treatment strategies is appropriate. Methods and Results. Clinical variables collected prospectively for the 3,339 patients of the Thrombolysis in Myocardial Infarction II study were analyzed retrospectively to identify predictors of clinical events at 42 day...

Background Although fingerstick is often favorably compared to venipuncture as a less invasive method of drawing blood for clinical labs, there little empirical research that compares physical and psychological stress responses vs. (blood draw using needle in the arm) within same person. Methods findings We assessed changes cortisol (a hormone), heart rate variability marker autonomic stress), ...

BACKGROUND: The role of sentinel lymph node biopsy (SLNB) in patients with an initial diagnosis of ductal carcinoma in situ (DCIS) has not been well defined. The purpose of our study was to determine when the risk of finding invasive disease on final pathology in patients with an initial diagnosis of DCIS was sufficiently high to justify use of SLNB. STUDY DESIGN: The records of 398 consecutive...

Background. Thrombolysis has altered treatment of acute myocardial infarction (AMI). Therefore, reevaluation of predictors of outcome and treatment strategies is appropriate. Methods and Results. Clinical variables collected prospectively for the 3,339 patients of the Thrombolysis in Myocardial Infarction II study were analyzed retrospectively to identify predictors of clinical events at 42 day...

the absence of cerebrospinal fluid (csf) pleocytosis in invasive meningococcal disease (imd) has been associated with an increased risk of death. it is unknown whether patients who lack a cellular response to central nervous system (cns) infection are at the same risk of adverse outcome as patiens without cns infection. to determine the frequency of presentation and outcome of three groups of c...

lactic acid bacteria which are  used  as  probiotics  have  ability to  modulate  immune responses and modify immune mechanisms. it has also been indicated that some strains of this family can affect the immune responses against solid tumors. in the present work, we proposed to study the effects of oral administration of l.cacesi ssp casei on the nk cells cytotoxicity and also production of cyt...

conclusion with thorough technical knowledge and an adequate learning curve, pra could serve as the surgeon’s preferred surgical approach to the adrenal gland within the confines of its selection criteria. background since the early 1990s, endoscopic adrenalectomy has become the gold standard surgical approach for the adrenal gland. also, lateral transperitoneal adrenalectomy (lta) which is the...

the alien polychaetes are widely distributed in the whole mediterranean sea as well as in theegyptian waters. the objective of this study is to highlight the distribution and abundance of the alienpolychaetes along the alexandria coast, their contribution to the total polychaete community and the changesthey caused in the community structure. through monthly sampling polychaetes were collected ...