نتایج جستجو برای: ischemia reperfusion injuries
تعداد نتایج: 209679 فیلتر نتایج به سال:
Introduction: Using brief episodes of ischemia and reperfusion (IR) prior to a more sustained IR insult – ischemic preconditioning (IPC) – can reduce IR injury of the heart, brain and many other tissues. The purpose of present study was to investigate the effect of 2min ischemic periods on subsequent rat renal IR injury. Methods: Male rat's renal IR injury was investigated in a right nephrectom...
Pervious studies have shown that pentoxifylline (PTX) has beneficial effects in reduction of stroke and brain trauma injuries in experimental animals. However, there is very little and controversial information about the effect of PTX on brain edema in cerebral ischemia. Therefore, the aim of this study was to determine the effects of different doses of PTX on brain edema and neurological m...
in the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. the hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. in the control group, the hearts were perfused by normal drug free krebs-henseleit (k/h) solution t...
Ischemia-reperfusion injury to the kidney is a complex pathophysiological process that has importance during transplantation as it affects graft function and survival. It starts with the physiological changes associated with the death of the donor, including the direct effects of hypoxia and metabolic stress. The injury continues through the organ procurement and preservation procedures. Upon r...
Background & Aims: Cerebral ischemia is known as a major worldwide problem and subsequent reperfusion leads to apoptosis or programmed cell death. Specific regions of the brain and specific types of neurons, including hippocampal CA1 pyramidal neurons are more sensitive in cerebral ischemia. Today cell therapy is one of the common treatments that spread among the researchers. In this study, we...
24 Ischemic pre(IPC) and postconditioning (IPO) protect the liver against 25 ischemia/reperfusion injuries. Conditioning involves several different trigger factors, 26 mediators and effectors, many of which are affected during the early phase of 27 reperfusion, ultimately resulting in decreased liver injuries. The aim of the present 28 study was to investigate the genomic response induced by IP...
Ischemic pre (IPC)- and postconditioning (IPO) protect the liver against ischemia/reperfusion injuries (IRI). Conditioning involves several different trigger factors, mediators, and effectors, many of which are affected during the early phase of reperfusion, ultimately resulting in decreased liver injuries. The aim of the present study was to investigate the genomic response induced by IPC and ...
Background and Objective: Ischemia plays a major role in development of pathological changes in various neuropathies. Reperfusion amplifies physiological and pathological abnormalities in ischemic nerves. In this research, we studied ischemic-reperfusion (IR) injury of sciatic nerve up to 14 days of reperfusion. Materials & Methods: IR was produced by ligation and release of nooses around suppl...
Background: The aim of this study was to investigate the short term protective effect of oxytocin on testicular ischemia reperfusion injury immediately after detorsion in a rat model. Materials and Methods: Twenty adult rats were randomly divided into four groups: Control, Ischemia- Reperfusion (IR), Oxytocin and IR+ Oxytocin. Testicular ischemia was achieved by torsion of the left testis 720° ...
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