In heterologous expression systems, KCNE2 has been demonstrated to interact with multiple α-subunits of voltage-dependent cation channels and modulate their functions. However, the physiological and pathological roles of KCNE2 in cardiomyocytes are poorly understood. The present study aimed to investigate the effects of bidirectional modulation of KCNE2 expression on action potential (AP) durat...

This paper presents the possibilities and properties of Indium tin oxide (ITO)covered quartz crystal as a NOx toxic gas-sensor. The starting sol-gel solution was prepared by mixing indium chloride dissolved in acetylacetone and tin chloride dissolved in ethanol (0-20% by weight). The ITO thin films were deposited on the gold electrodes of quartz crystal by spin-coating technique and subsequentl...

Wenckebach-like rhythms in isolated rabbit ventricular cells are characterized by beat-to-beat increments in action potential duration (APD) and latency, giving rise to a beat-to-beat decrease in the recovery interval and culminating in a skipped beat. These systematic APD changes are associated with a beat-to-beat decrease in the slope of the early repolarizing phase (phase 1) of the action po...

The objective of this work is the study and characterization of anodized indium tin oxide (anodized-ITO) as a sodium ion selective electrode and differential structures including a sodium-selective-membrane/anodized-ITO as sensor 1, an anodized-ITO membrane as the contrast sensor 2, and an ITO as the reference electrode. Anodized-ITO was fabricated by anodic oxidation at room temperature, a low...

A biofuel cell (BFC) cathode has been developed based on direct electron transfer (DET) of hemoglobin (Hb) molecules with an indium-tin-oxide (ITO) electrode and their electrocatalysis for reduction of hydrogen peroxide (H2O2). In this study, the ITO-coated glass plates or porous glasses were prepared by using a chemical vapor deposition (CVD) method and examined the electrochemical characteris...

Del Castillo V. Hypomelanosis of Ito: diagnostic criteria and report of 41 cases. Pediatric Dermatol 1992; 9: 1–10 2. David TJ. Hypomelanosis of Ito: a neurocutaneous syndrome. Arch Dis Child 1981; 56: 798–800 3. Coward RJM, Risdon RA, Bingham C, Hattersley AT, Woolf AS. Kidney disease in hypomelanosis of Ito. Nephrol Dial Transplant 2001; 16: 1267–1269 4. Chevalier C, Colon S, Faraj G, Bouvier...

Biomathematical models and experiments have indicated that passive extracellular conductors influence field stimulation. Because metallic conductors prevent optical mapping under the conductor, we have evaluated a passive translucent indium tin oxide (ITO) thin-film conductor to allow mapping of transmembrane potential (V(m)) and stimulatory current under the conductor. A 1-cm ITO disk was patt...

Shi, Hong, Hui-Zhen Wang, and Zhiguo Wang. Extracellular Ba21 blocks the cardiac transient outward K1 current. Am. J. Physiol. Heart Circ. Physiol. 278: H295–H299, 2000.—Ba21 is widely used as a tool in patch-clamp studies because of its ability to block a variety of K1 channels and to pass Ca21 channels. Its potential ability to block the cardiac transient outward K1 current (Ito) has not been...

We fabricate high-performance, flexible, transparent electrochromic (EC) films and thin film heaters (TFHs) on an ITO/Cu/ITO (ICI) multilayer electrode prepared by continuous roll-to-roll (RTR) sputtering of ITO and Cu targets. The RTR-sputtered ICI multilayer on a 700 mm wide PET substrate at room temperature exhibits a sheet resistance of 11.8 Ω/square and optical transmittance of 73.9%, whic...

Nowadays, the Latin American software industry, as it is mostly represented by Small and Medium Enterprises (SMEs), should focus on improving its service capacity towards high quality, low costs, and timely delivery. Within this context, SMEs providing Information Technology Outsourcing (ITO) services require information that allows to assess and monitor their contractual relationships and the ...