نتایج جستجو برای: jc virus
تعداد نتایج: 400574 فیلتر نتایج به سال:
Abstract Progressive multifocal leukoencephalopathy (PML) is a serious and often lethal demyelinating disease of the brain that develops almost exclusively in patients with severe immunosuppression. The caused by reactivation latent polyoma JC virus (JCV). PML occurs rarely non-hematologic malignancies, this report, authors present an uncommon case rapidly progressing, fatal patient advanced pr...
Two polyomaviruses, BK virus (BKV) and JC virus (JCV), are ubiquitous in the human population, generally infecting children asymptomatically and then persisting in renal tissue. It is generally thought that reactivation leads to productive infection for both viruses, with progeny shed in the urine. Several studies have shown that the rate of JC viruria increases with the age of the host, but a ...
Insulin receptor substrate 1 (IRS-1) is the major signaling molecule for the insulin and insulin-like growth factor I receptors, which transduces both metabolic and growth-promoting signals, and has transforming properties when overexpressed in the cells. Here we show that IRS-1 is translocated to the nucleus in the presence of the early viral protein-T-antigen of the human polyomavirus JC. Nuc...
AIMS Although the aetiology of medulloblastoma remains elusive, several lines of evidence suggest an association with the human neurotropic polyomavirus JC and its oncoprotein T antigen. The tumour forming properties of JC virus T antigen are the result, at least in part, of its ability to bind and inactivate tumour suppressor/cell cycle regulatory proteins, such as p53 and the retinoblastoma f...
Arboviruses isolated and identified from mosquitoes in South Carolina (USA) are described, including new state records for eastern equine encephalitis virus (EEE), St. Louis encephalitis virus (SLE), Flanders virus, Tensaw virus (TEN), and a variant of Jamestown Canyon virus (JC). Mosquitoes were collected at 52 locations in 30 of 46 South Carolina counties beginning in June 1996, and ending in...
(YGdSm)123 sample with nominal composition (Y0.33 Gd0.33 Sm0.33 )Ba 2 Cu 3 O X ,also YGdEu1 and YGdEu2 samples with nominal composition (Y0.33 Gd0.33 Eu0.33 )Ba2 Cu3 OX were prepared at different oxygenation conditions. All the samples were analysed by ac susceptibility , resistivity , critical current density (Jc), SEM,XRD and EDX. The critical current density measurements show that the Jc i...
1Department of Neurology and 2Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; 3St. Francis Hospital, Poughkeepsie, New York, USA; 4St. Luke’s Hospital, Newburgh, New York, USA; 5New England Medical Center, Boston, Massachusetts, USA; and 6Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Bosto...
Opportunistic infections continue to be a major cause of disease in patients with HIV infection. Despite the development of highly active antiretroviral therapy (HAART ) , opportunistic infections continue to be seen in patients who do not have access to antiretrovirals, and in patients who do not have an adequate response to antiretrovirals [1]. Viral infections are a major cause of opportunis...
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