BACKGROUND : Jet-lag commonly affects air travellers who cross several time zones. It results from the body's internal rhythms being out of step with the day-night cycle at the destination. Melatonin is a pineal hormone that plays a central part in regulating bodily rhythms and has been used as a drug to re-align them with the outside world. OBJECTIVES : To assess the effectiveness of oral me...

The chronotype, which reflects the circadian rhythm preferences of individuals in their daily activities and sleep-wake cycles, can be considered on a dimension extreme morningism eveningism. Individuals with morning evening chronotypes face many physical psychological dangers due to accumulated sleep debt, short total time insufficient efficiency. In chronotypes, especially people, social jet-...

Disruptions in circadian rhythms, as seen in human shift workers, are often associated with many health consequences including impairments in cognitive functions. However, the mechanisms underlying these affects are not well understood. The objective of the present study is to explore the effects of circadian disruption on hippocampal neurogenesis, which has been implicated in learning and memo...

OPINION STATEMENT With the growth of the 24-hour global marketplace, a substantial proportion of workers are engaged in nontraditional work schedules and frequent jet travel across multiple time zones. Thus, shift work disorder and jet lag are prevalent in our 24/7 society and have been associated with significant health and safety repercussions. In both disorders, treatment strategies are base...

already extensive evidence from fMRI and architectonic studies that the human brain contains many more cortical areas (possibly 150 or more) than the brains of macaque monkeys. One would also expect areas to be more frequently subdivided into sets of modules or columns of functionally related neurons, such as the three types of bands of neurons subdividing the second visual area, V2, of primate...

Professor, Behavioral Sciences Dept., Rush University Medical Center, Chicago Director, Biological Rhythms Research Laboratory, Rush University Medical Center Associate Professor, Behavioral Sciences Dept., Rush University Medical Center, Chicago Associate Director, Biological Rhythms Research Laboratory, Rush University Medical Center Corresponding author for proofs and reprints: Charmane I. E...