A graph H is single-crossing if it can be drawn in the plane with at most one crossing. For any single-crossing graph H, we give an O(n4) time algorithm for counting perfect matchings in graphs excluding H as a minor. The runtime can be lowered to O(n1.5) when G excludes K5 or K3,3 as a minor. This is the first generalization of an algorithm for counting perfect matchings in K3,3free graphs (Li...

AIM Thymic epithelial cells (TECs) are thought to play an essential role in T cell development and have been detected mainly in mice using lectin binding and antibodies to keratins. Our aim in the present study was to create a precise map of rat TECs using antibodies to putative markers and novel monoclonal antibodies (i.e., ED 18/19/21 and anti-CD205 antibodies) and compare it with a map from ...

The purpose of this study was to determine the effect garlic-based herbs (combinatioan with shallot, Kaempferia galanga , ginger, betel leaf, turmeric, Curcuma zanthorrhiza Alpinia lemongrass and coriander) solution as drinking water during broiler raising on content, pH cooking loos value meat. research design used a CRD 7 treatments 3 replications. dose ingredients 25% daily requirement. resu...

We give complete sequent-like tableau systems for the modal logics KB, KDB, K5, and KD5. Analytic cut rules are used to obtain the completeness. The systems have the analytic superformula property and can thus give a decision procedure.

1RXS J201607.0+251645 is identified to be an eclipsing binary. We present the preliminary observations in V band with the 0.6-m telescope for three years and the extensive observations in V and R band with the 0.8-m telescope for six nights, respectively. The light curve of the system is EB type. Five light minimum times were obtained and the orbital period of 0. 388058(±0. 00044) is determined...

beta-catenin signaling is one of the key factors regulating the fate of hair follicles (HFs). To elucidate the regulatory mechanism of embryonic HF fate determination during epidermal development/differentiation, we analyzed conditional mutant mice with keratinocytes expressing constitutively active beta-catenin (K5-Cre Catnb(ex3)fl/+). The mutant mice developed scaly skin with a thickened epid...

Transgenic mice (K5-PKC alpha) in which the keratin 5 promoter directs the expression of protein kinase C-alpha (PKC alpha) to epidermal keratinocytes display a 10-fold increase in PKC alpha protein in their epidermis and alterations in phorbol ester-induced cutaneous inflammation [J Cell Science 1999;112:3497-3506]. In the current study, we have used these K5-PKC alpha mice to examine the role...

The proto-oncogene c-myc encodes a transcription factor that is implicated in the regulation of cellular proliferation, differentiation, and apoptosis and that has also been found to be deregulated in several forms of human and experimental tumors. We have shown that forced expression of c-myc in epithelial tissues of transgenic mice (K5-Myc) resulted in keratinocyte hyperproliferation and the ...

Based on gene expression patterns, breast cancers can be divided into subtypes that closely resemble various developmental stages of normal mammary epithelial cells (MECs). Thus, understanding molecular mechanisms of MEC development is expected to provide critical insights into initiation and progression of breast cancer. Epidermal growth factor receptor (EGFR) and its ligands play essential ro...

IL22 signaling plays a critical role in the pathogenesis of skin inflammatory diseases such as psoriasis and atopic dermatitis. Smad7 is transforming growth factor β (TGFβ) inhibitor consisting an N-terminal domain, C-terminal linker region harboring PY motif. transgene expression Keratin 5 (K5)+ keratinocytes attenuated K5.TGFβ1 transgene-induced psoriatic inflammation. The downstream mechanis...