The development of an efficient protocol for successful hairy root induction by Agrobacterium rhizogenes is the key step toward an in vitro culturing method for the mass production of secondary metabolites. The selection of an effective Agrobacterium strain for the production of hairy roots is highly plant species dependent and must be determined empirically. Therefore, our goal was to investig...

Primula veris L. and Primula elatior (L.) Hill represent medicinal plants used for the production of herbal teas and preparations with antioxidant and expectorant activity. Flowers and roots of both species possess the same biological activity. In the presented study, raw materials of wild growing P. veris and P. elatior were compared in terms of the content and composition of phenolic compound...

The interest in phenols and anthocyanins has increased due to their antioxidant properties and to their potential usage as dietary antioxidants in human nutrition. Total phenols and anthocyanin content, composition and stability in berry extracts of blackcurrant interspecific hybrids, and antioxidative activity of extracts was evaluated. Berries of interspecific hybrids accumulated 530 to 614 m...

The phenolic profile of Amazon grape fruit (Pourouma cecropiifolia Martius) was investigated by high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-ESI-MS/MS). For this purpose, suitable extraction and liquid chromatographic methods were developed. Anthocyanins, flavonols and chlorogenic acids were found mainly in the peel. Besides the main anthocyanins, i.e. ...

The aim of this study was to evaluate the content and profile phenolic compounds (PCs) antioxidant properties field-grown leaves, in vitro leaves callus cultures blackberry ‘?a?anska Bestrna’ blueberry ‘Toro’. In shoots selected genotypes were grown either on original Murashige Skoog (MS) medium containing 1 mg/L BA, 0.1 IBA GA3 (‘?a?anska Bestrna’) or MS with macroelements reduced ½, 2 zeatin ...

The effects of eleven flavonoids on lipid peroxidation, protein degradation, deformability and osmotic fragility of human erythrocytes exposed in vitro to 10 mM H2O2 for 60 min at 37 ̊C have been studied. The following flavonoids; quercetin, rutin and morin significantly protected erythrocytes against lipid peroxidation caused by H2O2. This inhibition of lipid peroxidation could be explained by ...

The recent outbreak of the respiratory pandemic known as novel coronavirus SARS-CoV-2 disease “COVID-19” was first identified in Wuhan, China and quickly spread to other countries. 3CL protease (3CLpro) enzyme is main SARS-CoV-2, which responsible for replication therefore, 3CLpro considered a drug discovery target. study reports that molecular docking approach 30 compounds had been from Allium...

Radiation-induced oxidative stress and haematopoietic genomic instability is the major concern during planned or unplanned exposure. Use of natural phytochemicals an emerging strategy to prevent from harmful effects radiation. In current investigation, Quercetin 3-Rutinoside (Q-3-R), a polyphenolic bioflavonoid, has been evaluated against gamma radiation (2Gy) induced genotoxic damage imbalance...

The genus Stapelia belongs to the family Asclepiadaceae, which comprises a group of some 50 species, which have been used in medicine for their anti-inflammatory and antiarithritic properties . The presence of alkaloids in the genus Stapelia was first reported by Keller , where hordenine was isolated from the aerial part of S. gigantea. In addition, Meyer et al. reported the detection of N -met...