A 13 years old girl was admitted to the pediatric ward of hospital  No 1 of Kerman university of medical sciences because of crampy pains, pins and needles sensation of the extremities and history of an episode of seizure. Her problem started one week prior to admission with pain in the leg muscles, flexion of the fingers followed by seizure. On physical examination, the prominent finding inclu...

BACKGROUND Wilson's disease is a rare but treatable condition that often presents diagnostic dilemmas. These dilemmas have for the most part not been resolved by the identification and cloning of the Wilson's disease gene. AIMS To report our experience over three decades with patients with Wilson's disease in order to illustrate the diverse patterns of presentation and thereby broaden the app...

In the days leading up to the 2008 Olympic Games in Beijing, a number of scientific journals published special issues (1, 2 ) or critical commentaries and opinion pieces regarding the antidoping movement. For example, an analysis of antidoping policy by Kayser and Smith (3 ) presented criticisms based on ethical arguments (4 ). On the other hand, equally persuasive ethical arguments supporting ...

In an effort to boost meeting productivity and success, managers may employ trained group facilitators. They may also implement group Introduction Face-to-face meetings serve as a venue to bring together organizational eaders for decision making, issue tracking, policy setting, and a variety of activities aimed at adding reliability and flexibility in response to the ever-changing business envi...

Written February 1998 by B. Kayser (NSF). While there is no unequivocal evidence for neutrino mass, it is natural to suspect that the neutrinos, like the charged leptons and the quarks, have nonzero masses. Evidence of these masses is being sought through experiments on neutrinos created astrophysically, in the earth's atmosphere, by accelerators, by reactors, and by nuclear decays, and in stud...

Introduction and Genetics Wilson's disease (WD; Hepatolenticular degeneration) is an autosomal-recessive disorder of copper metabolism due to absence or dysfunction of a copper-transporting, Ptype ATPase which is essential for the transport of copper into bile. Affected patients accumulate excessive copper within the liver as well as the brain and other tissues. This is mainly a disease of chil...

BACKGROUND Liver transplantation is indicated for patients with Wilson's disease (WD) who present either with acute liver failure or with end-stage liver disease and severe hepatic insufficiency as the first sign of disease. However, almost all reported cases have been treated with death donor liver transplantation. Here we report the case of a patient with WD associated with fulminant hepatic ...