Masseter muscle hypertrophy is a rare condition of idiopathic cause. It clinically presents as an enlargement of one or both masseter muscles. Most patients complain of facial asymmetry; however, symptoms such as trismus, protrusion, and bruxism may also occur. Several treatment options reported for masseter hypertrophy are present, which range from simple pharmacotherapy to more invasive surgi...

A 32-year-old woman and a 50-year-old man with clinically typical Bethlem myopathy developed seemingly spontaneous keloids on their shoulder region (figure). The patients did not recall any significant trauma to the skin of this region. Bethlem myopathy (MIM #158810) is caused by dominant and recessive mutations in the collagen VI genes: COL6A1, COL6A2, and COL6A3. Skin manifestations include h...

Therapy for large symptomatic keloids is often plagued with complicated reconstruction manner and recurrence. This article reports a rare treatment combination for a chest keloid with internal mammary artery perforator flap reconstruction and radiation therapy. We excised the keloid and covered the defect with an internal mammary artery perforator flap. Immediate electron-beam irradiation thera...

Keloids develop when scar tissue responds to skin trauma with proliferative fibrous growths that extend beyond the boundaries of the original wound and progress for several months or years. Keloids most frequently occur in individuals of indigenous sub-Saharan African origin. The etiology for keloids is still unknown and treatment can be problematic as patients respond differently to various tr...

BACKGROUND Keloids and hypertrophic scars result from aberrant wound healing and remain a potential complication of any surgical procedure or trauma. Investigation of aberrant wound healing has been limited to the study of growth factors, collagen precursors, and DNA synthesis in simple in vitro systems, which necessitate removal or destruction of cells or factors in the growth environment of c...

Background Keloid is a unique refractory syndrome characterized by proliferation disorder of the fibroblasts. Recently, photodynamic therapy (PDT) has become promising technique to modulate However, use photosensitizer Phenalen-1-one (Ph1) in PDT for keloid remains be explored. Objectives This study investigated efficacy Ph1-PDT vitro and vivo models keloid. Material methods Cell viability was ...

Keloid disease is a fibro-proliferative disorder characterized by excessive deposition of collagen. Keloids has shown high recurrence rate. We undertook this study to determine what factors influence the with aim developing keloid scoring system. This was cohort prospective longitudinal patients who presented keloids, managed surgical excision followed post radiotherapy. Post-surgery were up fo...

In 2006, we established a scar/keloid-specialized unit in the Department of Plastic, Reconstructive, and Aesthetic Surgery at Nippon Medical School (NMS) Tokyo, Japan. ensuing 15 years, treated approximately 2,000 new scar/keloid patients annually. This extensive experience has greatly improved efficacy treatments offer. Therefore, discuss here latest NMS protocol for preventing treating keloid...

BACKGROUND Keloid is a benign fibrous growth, which presents in scar tissue of predisposed individuals. It is a result of irregular wound healing, but the exact mechanism is unknown. However, several factors may play a role in keloid formation. To date, there are no studies of keloids in Syria, and limited studies on Caucasians, so we have investigated the risk factors of keloids in Syrians (Ca...

Lacaziosis or Jorge Lobo's disease is a fungal, granulomatous, chronic infectious disease caused by Lacazia loboi, which usually affects the skin and subcutaneous tissue. It is characterized by slow evolution and a variety of cutaneous manifestations with the most common clinical expression being nodular keloid lesions that predominate in exposed areas. We report the case of a patient who had a...