PURPOSE To improve the visual acuity of patients with progressive keratectasia following laser in situ keratomileusis (LASIK). METHODS Five eyes of four patients underwent penetrating keratoplasty for ectasia after LASIK: In one patient the second eye was operated on 10 months after the first keratoplasty. The pre- and postoperative refraction, best spectacle-corrected visual acuity, and topo...

AIMS To describe the fitting of patients with high or irregular astigmatism following penetrating keratoplasty with contact lenses and to answer the question whether or not contact lenses with special back surface design can improve visual acuity in complex cases after penetrating keratoplasty. METHODS 28 eyes were included. They were fitted with contact lenses with a special back surface tha...

PURPOSE To compare outcomes after Descemet Membrane Endothelial Keratoplasty (DMEK) and traditional Descemet Stripping Endothelial Keratoplasty (DSEK) during the surgeon's DMEK learning curve in a prospective, non-randomized, consecutive, interventional case series. METHODS Consecutive patients presenting to the university eye clinics and undergoing endothelial keratoplasty were included. Dat...

PURPOSE To evaluate the anatomic and functional results of optical pachymetry-guided custom excimer laser-assisted lamellar keratoplasty in keratoconus patients. SETTING Eye Clinic, University of L'Aquila, L'Aquila, Italy. DESIGN Prospective noncomparative case series. METHODS Patients with keratoconus having unilateral surgery using custom excimer laser-assisted lamellar keratoplasty wer...

Here we report a case of endothelial keratoplasty with infant donor tissue obtained after brain death. A 52-year-old man with endothelial dysfunction of unknown cause in the right eye underwent non-Descemet stripping automated endothelial keratoplasty (nDSAEK) with tissue from an infant donor (2 years). Intraoperative and postoperative complications were recorded. Best corrected visual acuity a...

Stenotrophomonas maltophilia (S. maltophilia) is an emerging opportunistic ocular pathogen that should be included in the diff erential diagnosis of progressive keratitis in penetrating keratoplasty. Prognosis is poor because of the existence of co-infections and high antibiotic resistance. Th e present study reports two cases of keratitis caused by S. maltophilia in patients with penetrating k...

343 The emergence of endothelial keratoplasty (EK) represents the beginning of a new era in the treatment of corneal endothelial disorders which continues to evolve. Fifteen years ago we were performing penetrating keratoplasty for Fuchs’ dystrophy and bullous keratopathy but nowadays we are performing selective replacement of the diseased endothelial layer. In recent years two techniques of EK...

PURPOSE To evaluate the combined effect of conductive keratoplasty (CK) followed by corneal collagen cross-linking (CXL) in 2 patients with keratoconus. METHODS CK spots were applied on the flatter side of the cornea followed by CXL using riboflavin and UV-A light. RESULTS Immediately after CK, a significant corneal topographic improvement was observed. The CK effect regressed 3 months post...

PURPOSE To evaluate the intraoperative changes in the donor lenticule, recipient cornea, and the reduction of interface fluid thickness during Descemet's stripping and automated endothelial keratoplasty with EndoGlide™ (Angiotech Pharmaceuticals Inc, Vancouver, Canada) donor insertion, using intraoperative spectral-domain optical coherence tomography. METHODS Prospective observational case se...

D escemet membrane endothelial keratoplasty (DMEK), the newest and most advanced form of endothelial transplantation, represents the culmination of the evolution of keratoplasty techniques. It has nudged aside its predecessor, Descemet stripping automated endothelial keratoplasty (DSAEK), just as DSAEK displaced its own forerunner, deep lamellar endothelial keratoplasty (DLEK). What differentia...