نتایج جستجو برای: ki67 expression
تعداد نتایج: 873918 فیلتر نتایج به سال:
Background: The biological basis for the superior efficacy of neoadjuvant letrozole versus tamoxifen for postmenopausal women with estrogen receptor (ER)-positive locally advanced breast cancer was investigated by analyzing tumor proliferation and expression of estrogen-regulated genes before and after the initiation of therapy. Methods: Tumor samples were obtained at baseline and at the end of...
OBJECTIVE Restenosis after percutaneous coronary intervention remains to be a serious medical problem. Although mineralocorticoid receptor (MR) has been implicated as a potential target for treating restenosis, the cellular and molecular mechanisms are largely unknown. This study aims to explore the functions of macrophage MR in neointimal hyperplasia and to delineate the molecular mechanisms. ...
FGF-16 has been reported to be preferentially expressed in the adult rat heart. We have investigated the expression of FGF-16 in the perinatal and postnatal heart and its functional significance in neonatal rat cardiac myocytes. FGF-16 mRNA accumulation was observed by quantitative RT-PCR between neonatal days 1 and 7, with this increased expression persisting into adulthood. FGF-2 has been sho...
AIMS To examine thymomas for proteins encoded by oncogenes and to determine whether their presence correlates with tumour growth and associated myasthenia gravis. METHODS Sections of 24 thymomas were incubated with anti-EGF receptor (EGF-R), anti-Ki67 antigen, anti-p53, and anti-bcl-2 antibodies, and then stained using the alkaline phosphatase/anti-alkaline phosphatase (APAAP) technique. Cell...
PURPOSE Pathological vascular differentiation in retinal vein occlusion (RVO)-related neovessel formation remains poorly characterized. The role of intraocular lymphatic-like differentiation or endothelial progenitor cell activity has not been studied in this disease. METHODS Vitrectomy was performed in an eye with hemi-RVO; the neovessel membrane located at the optic nerve head was removed a...
Angiogenesis, development of new blood vessels from previous blood vessels, is necessary for tumor growth and metastasis. During recent years, a lot of effort has been put into identifying markers of angiogenesis (Meng et al., 2012). CD105 is not only a marker that has an important role in angiogenesis (Nassiri et al., 2011) but also it is essential for proliferation of endothelial cells and st...
Colorectal cancer (CRC) is one of the most frequent malignancies and third cause death from globally. To increase prognosis prediction in patients with CRC, understanding prognostic marker crucial, especially patient advanced stages. Several studies have reported value Ki67 expression cancer. However, only few on role CRC exist, partially shown contradictory results. The aim this study to compa...
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