BACKGROUND Inherited epidermolysis bullosa (EB) is a group of skin diseases characterized by blistering of the skin and mucous membranes.There are four major types of EB (EB simplex, junctional EB, dystrophic EB and Kindler syndrome) caused by different gene mutations. Dystrophic EB is derived from mutations in the type VII collagen gene (COL7A1), encoding a protein which is the predominant com...

The number of young dual language learners (DLLs) 1 enrolling in early childhood programs has increased steadily over the last 15 years, a trend that is expected to continue. A factor contributing to this trend is the rapid growth of the immigrant population. As of 2005, one in four, or 25%, of young children in the United States were children of immigrant families (Hernandez, Denton, & Macartn...

Khot, Kindler, Mossel and O’Donnell [KKMO04] showed a reduction from the UniqueGame problem to the problem of approximating MaxCut for any approximation that is even slightly better than the efficient algorithm of Goemans & Williamson [GW95]. A most interesting and important open problem is whether there exists an efficient reduction in the other direction. Such a reduction would imply that the...

The main result of this paper is an explicit disperser for two independent sources on n bits, each of min-entropy k = 2 1−α0 , for some small absolute constant α0 > 0). Put differently, setting N = 2 and K = 2, we construct an explicit N ×N Boolean matrix for which no K ×K sub-matrix is monochromatic. Viewed as the adjacency matrix of a bipartite graph, this gives an explicit construction of a ...

Lichen sclerosus et atrophicus was first described by Hallopeau (1887), who regarded it as a variant of lichen planus. Ormsby (1910), however, considered it to be a separate disease entity. Stuhmer (1928) used the term "balanitis xerotica obliterans" to describe a case in which there was progressive sclerosis and atrophy of the glans penis and preputial remains following an operation for congen...

La epidermólisis bullosa (EB) es un grupo heterogéneo de trastornos hereditarios caracterizado por aumento la fragilidad mucocutánea. El objetivo del presente estudio describir las características clínicas y epidemiológicas los pacientes con EB atendidos en el Hospital Universitario Paz, centro referencia nacional para hereditaria. Estudio observacional, retrospectivo unicéntrico. Se incluyeron...

2. Johne R, Plenge-Bonig A, Hess M, Ulrich RG, Reetz J, Schielke A. Detection of a novel hepatitis E–like virus in faeces of wild rats using a nested broad-spectrum RT-PCR. J Gen Virol. 2010;91:750–8. http://dx.doi.org/10.1099/vir.0.016584-0 3. Li TC, Yoshimatsu K, Yasuda SP, Arikawa J, Koma T, Kataoka M, et al. Characterization of self-assembled virus-like particles of rat hepatitis E virus ge...