The success of oncolytic virotherapies depends on the tumour microenvironment, which contains a large number infiltrating immune cells. In this theoretical study, we derive an ODE model to investigate interactions between breast cancer cells, virus (Vesicular Stomatitis Virus), and tumour-infiltrating macrophages with different phenotypes can impact dynamics viruses. complexity requires combine...

Tuberculous pleuritis (TP) is one of the most common extra-pulmonary tuberculosis form. Because tuberculous pleurisy hard to diagnose due slow course disease and lack specificity in symptoms diagnostic methods. In that reason, we need multidisciplinary approach efficient biomarkers. Acid-fast bacilli (AFB) staining, cultures pathophysiological biopsy finding from majority patients are positive ...

BACKGROUND Mycobacterium marinum is a human opportunistic pathogen that is known to inhabit swimming pools, home aquariums, and natural bodies of salt and fresh water. Epidemic cases involving swimming pools are easily recognized, but sporadic cases are frequently misdiagnosed. OBJECTIVE A 42-year-old male presented with a 2-month history of the appearance of livid, verrucous, painless nodule...

Vulvar cancer accounts for less than 1% of malignancies in women. Verrucous carcinoma of the vulva is a rare histological variation, comprising less than 1% of vulvar cancer cases. Although it is characterized as being locally invasive, the condition is not associated with metastatic spreading. Lesions present in the form of a verrucous, ulcerated, and bleeding tumor that can reach large dimens...

A new taxon of sphenosuchian crocodylomorph, Dromicosuchus grallator, is described on the basis of a well-preserved, largely articulated partial skeleton from Late Triassic strata in the Durham sub-basin of the Deep River basin (Newark Supergroup) of Durham County, North Carolina. The holotype was preserved directly beneath the skeleton of a rauisuchian archosaur; this association, along with a...

This study assessed the performance of a rapid, low-cost, colorimetric method, the resazurin microtitre assay (REMA) plate method, for the detection of resistance to isoniazid and rifampicin in 136 clinical isolates of Mycobacterium tuberculosis from two hospitals in Algiers. MICs were determined and the results were compared with those obtained with the conventional proportion method on Löwens...

First described in 1925, giant condyloma acuminatum also known as Buschke-Löwenstein tumor (BLT) is a benign, slow-growing, locally destructive cauliflower-like lesion usually in the genital region. The disease is usually locally aggressive and destructive with a potential for malignant transformation. The causative organism is human papilloma virus. The most common risk factor is immunosuppres...