Doctoral level scientists often pursue a traditional academic route, focusing their efforts on research and education. However, additional options exist for those that are interested in using their laboratory and research skills in a clinical setting. Clinical laboratory directors serve as the interface between the clinical laboratory and the users of laboratory test results. This article descr...

am engaged almost in a work of supererogation when I presume to speak upon a topic so familiar to you all. Despite this feeling on my part, I am led to believe that upon occasion an oft-told tale, if palatably redressed, may prove appetizing enough: I will venture an experiment. A careful perusal of the pages of the history of medicine plainly demonstrates the long and tortuous path pursued fro...

The examples of concepts are : (1) Collagen Diseases. Attempts have been made to bring many apparently unconnected diseases under the basic pathology of a morbid state of the connective tissue. All of them have been benefited, permanently or temporarily by cortisone and ACTH. (2) Types of Anaemia. This is the main item under the haemopoietic system which has been reviewed. Davidson's classifica...

Pregnancy-related disorders which typically include gestational or pregnancy diabetes, hypertensive or high blood pressure-related conditions (i.e., chronic hypertension, preeclampsia-eclampsia, preeclampsia superimposed on chronic hypertension and gestational hypertension), stillbirth and abnormal size of babies at birth (top and bottom 10 % in weight) offer an invaluable opportunity for diagn...

Pediatric medicine that spans from the perinatal period through adolescence is a field in its own right, as it requires knowledge about early growth and development that are not present in adult medicine. Indeed, it is during these crucial years that adult health and wellbeing are being carved. This statement is supported by epidemiological studies and meta-analyses indicating that many adult d...

to the probability of discrepancy and thus to the power of this method: the power will be higher if the number of blood groups is higher or if the frequencies are more similar. check method for detecting specimen mix-up. To the Editor: Dr. Keffer (1) has provided a thought-provoking report on the noncompliance of physicians with most clinical practice guidelines (CPGs). He also refers to the La...

An immunosensor is a device comprising an antigen or antibody species coupled to a signal transducer, which detects the binding of the complementary species. An indirect immunosensor uses a separate labeled species that is detected after binding by, e.g., fluorescence or luminescence (i.e., a heterogeneous immunoassay). A direct device detects the binding by a change in potential difference, cu...

BACKGROUND Clinical Governance is described as "a framework through which the NHS organisations are accountable to continue to improve the quality of the service and safeguarding high standards of care by creating an environment in which excellence in clinical care would flourish"; it is aimed to ensure continuous improvement in the overall standard of clinical care, ensuring that clinical deci...

We studied whether laboratory confirmation of heparin-induced thrombocytopenia (HIT) can be improved after antigen clearance by determining free antibody and combining the results of an antigenic and a biologic assay. Blood samples taken over 40 days in 14 patients with HIT with thromboembolism underwent fluorescence-linked immunofiltration and the carbon 14–serotonin release assays. Of the 14 ...

Dong-Won Yoo, M.D., Sang Hyuk Park, M.D., Jongyoun Yi, M.D., In-Suk Kim, M.D., Hyung-Hoi Kim, M.D., Chulhun L. Chang, M.D., and Eun Yup Lee, M.D. Department of Laboratory Medicine, Pusan National University School of Medicine, Pusan National University Yangsan Hospital, Yangsan; Department of Laboratory Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan; Departm...