D. Schaub, A. K. Weiss, J. W. Kaiser, A. Petritoli, A. Richter, B. Buchmann, and J. P. Burrows Swiss Federal Laboratories for Materials Testing and Research (EMPA), Ueberlandstrasse 129, CH-8600 Duebendorf, Switzerland Remote Sensing Laboratories, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland Institute of Atmospheric Science and Climate (ISAC-CNR), Via Gobetti 101, ...

We developed an easy MALDI-TOF MS-based assay to identify microorganisms directly from thioglycolate broth. A total of 101 positive thioglycolate broths inoculated with 15 different kinds of samples were evaluated. In 91 samples (90.1%), direct MALDI-TOF MS identifications were the same as those obtained after conventional laboratory procedures including subcultures. In 10 samples misidentified...

Documentation of research data plays a key role in the biomedical engineering innovation processes. It makes an important contribution to the protection of intellectual property, the traceability of results and fulfilling the regulatory requirement. Because of the increasing digitalization in laboratories, an electronic alternative to the commonly-used paper-bound notebooks could contribute to ...

The need for a practical method of control of Salmonella infections in colonies of laboratory mice has long been emphasized both by research workers and by commercial breeders of mice. Although various methods have been suggested from time to time, such proposals have not resulted in any consistent long-term practical control of paratyphoid infection. Some of the proposed procedures of paratyph...

The emergence of the laboratory mouse as a favored species for genetic research has posed a number of problems for scientists interested in the reflection of genetic influences in mouse behavior. It is commonly thought that rat behavior, which has been studied more extensively than mouse behavior, could be easily generalized to mice. In this article, a number of categories of behavior displayed...

Laboratory mouse strains carry endogenous copies of the xenotropic mouse leukemia viruses (X-MLVs), named for their inability to infect cells of the laboratory mouse. This resistance to exogenous infection is due to a nonpermissive variant of the XPR1 gammaretrovirus receptor, a resistance that also limits in vivo expression of germ line X-MLV proviruses capable of producing infectious virus. B...

The series of papers in this issue reflects the present state of knowledge on opportunistic infections of laboratory rodents and provides speculation into where the field is headed. What has not been covered is the phenomenal growth in knowledge of murine infectious diseases over the last 50 yr. Remarkably, more than 60 genera of overtly or opportunistically pathogenic viruses, bacteria, fungi,...

We report the construction of a genetic linkage map of the mouse, consisting entirely of genetic markers that can be rapidly typed by polymerase chain reaction and that show a high degree of polymorphism among inbred laboratory strains. Specifically, the map contains 317 simple sequence length polymorphisms at an average spacing of 4.3 cM and is detectably linked to approximately 99% of the mou...