AIM To compare the performance of a new chromogenic agar medium CHROMagar ESBL (KC-ESBL) to chromID ESBL (SB-ESBL) for the detection and presumptive identification of extended-spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae directly from clinical specimens. METHODS AND RESULTS A total of 256 specimens were screened for ESBL producers. Also, the genotypes of the ESBLs and plasmid-medi...

Definitions: Beta-lactam antimicrobials are characterized by having a four-membered cyclic amide (beta-lactam ring) as part of their chemical structure (Figure 1) [1]. This broad group includes the penicillins, cephalosporins, carbapenems, and monobactams [1]. All beta-lactams have a similar mechanism of action; they inhibit bacterial cell wall synthesis [1]. Resistance to beta-lactam antimicro...

The purpose of the study was to examine prevalence Escherichia coli in shrimps and mussels, determine distribution β-lactam, aminoglycoside, quinolone, multi-drug resistance phenotypically genotypically E. isolates obtained from mussels Istanbul. Faecal samples were collected (n = 96) Marmara Sea coastline fish markets For detection antibiotic susceptibilities, seven groups used. β-lactam...

BACKGROUND Studies about transmission rates of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in hospitals and households are scarce. METHODS Eighty-two index patients with new carriage of ESBL-producing Escherichia coli (ESBL-Ec; n = 72) or ESBL-producing Klebsiella pneumoniae (ESBL-Kp; n = 10) and their hospital (n = 112) and household (n = 96) contacts were studied prosp...

background and objectives: β-lactamase production is the predominant mechanism for resistance to β-lactams in enterobacteriaceae. the producing isolates are often multidrug resistant and are major hosts for extended spectrum β-lactamases. this study was designed to determine the prevalence of extended-spectrum β-lactamase producing isolates of escherichia coli and klebsiella pneumoniae and thei...

extended-spectrum β-lactamase (esbl)-producing enterobacteria has become a considerable global concern because of their potential dissemination in humans, in domestic animals, wildlife and the environment. the present study aimed to explore the esbl producing  enterobacteria in aquatic sources of bangladesh as the water may be the potential source of dissemination of this alarming antimicrobial...

BACKGROUND Pseudomonas aeruginosa is an important nosocomial pathogen characterized by its innate resistance to multiple antimicrobial agents. Plasmid-mediated drug resistance also occurs by the production of extended-spectrum β-lactamases (ESBL), metallo β-lactamases (MBL), and AmpC β-lactamases. Another important factor for establishment of chronic infections by P. aeruginosa is biofilm forma...

Corresponding Author: Viera Lovayová Department of Public Health and Hygiene, Faculty of Medicine, University of P.J. Safarik in Košice, Trieda SNP 1, 040 11 Košice, Slovakia Phone: +421915932031 Email: [email protected] Abstract: The beta-lactamases with extended spectrum of activity (ESBL) are medically one of the most important group of enzymes. The presented study provides identificati...

conclusions this study showed that multiple β-lactamases can be produced in burn isolates. this suggests that use of cephalosporins and carbapenems should be restricted in burn isolates to minimize the development and spread of these multidrug resistant pathogens. results there was 99% resistance to carbenicillin, and ticarcillin, 98% to cotrimoxazole, 96% to ciprofloxacin, and aztreonam, 95% t...