PURPOSE There is a need for new technologies to study tissue-based biomarkers. The current gold standard, immunohistochemistry, is compromised by variability in tissue processing and observer bias. Reverse transcription-PCR (RT-PCR), immunocytochemistry, and reverse-phase lysate microarrays (RPM) are promising alternative technologies but have not yet been validated, or correlated, on the same ...

We developed an immunochromatography-based assay for detecting antibodies against recombinant α-galactosidase A proteins in serum. The evaluation of 29 serum samples from Fabry patients, who had received enzyme replacement therapy with agalsidase alpha and/or agalsidase beta, was performed by means of this assay method, and the results clearly revealed that the patients exhibited the same level...

The usefulness of the measurement of urinary lactoferrin (LF) released from polymorphonuclear leukocytes and of an immunochromatography test strip devised for measuring urinary LF for the simple and rapid diagnosis of urinary tract infections (UTI) was evaluated. Urine specimens were collected from apparently healthy persons and patients diagnosed as suffering from UTI. In the preliminary study...

The presence of a columnar or clustered organization for some property often denotes that this property is important to the local information processing in a cortical area. To determine whether self-motion is systematically organized in the ventral intraparietal area (VIP), we made long electrode penetrations, recording both multi-unit and single-unit tuning for horizontally varying heading sti...

Self-motion detection requires the interaction of a number of sensory systems for correct perceptual interpretation of a given movement and an eventual motor response. Parietal cortical areas are thought to play an important role in this function, and we have thus studied the encoding of multimodal signals and their spatiotemporal interactions in the ventral intraparietal area of macaque monkey...

The prevalence of Adenovirus was determined among children with gastroenteritis/ diarrhea in Warri, Southern, Nigeria. Adenovirus was detected using a lateral flow immunochromatographic test kit (Gastro Vir-Strip, Coris Bioconcept, Belgium). The prevalence of Adenovirus was 11 (14.7%) and there were no association with age and gender of subjects. There is need for routine screening of Adenoviru...