BACKGROUND Women are more likely to develop cancer in the left breast than the right. Such laterality may influence subsequent management, especially in elderly patients with heart disease who may require radiation therapy. The purpose of this study was to explore possible factors for such cancer laterality. METHODS In this work, clinical data for consecutive patients with histologically conf...

The ventral premotor cortex (PMv) and the primary motor cortex (MI) of monkeys participate in various sensorimotor integrations, such as the transformation of coordinates from visual to motor space, because the areas contain movement-related neuronal activity reflecting either visual or motor space. In addition to relationship to visual and motor space, laterality of the activity could indicate...

BACKGROUND Functional movement tests that are predictive of injury risk in National Collegiate Athletic Association (NCAA) athletes are useful tools for sports medicine professionals. The Lower Quarter Y-Balance Test (YBT-LQ) measures single-leg balance and reach distances in 3 directions. PURPOSE To assess whether the YBT-LQ predicts the laterality and risk of sports-related lower extremity ...

The significant morbidity and mortality associated with laterality disease almost always are attributed to complex congenital heart defects (CHDs), reflecting the extreme susceptibility of the developing heart to disturbances in the left-right (LR) body plan. To determine how LR positional information becomes ;translated' into anatomical asymmetry, left versus right side cardiomyocyte cell line...

BACKGROUND Reduced overall survival has been observed in patients with left-sided versus right-sided breast cancer due to cardiac toxicity after radiotherapy. However, the effect of laterality and primary tumor site on breast cancer-specific mortality (BCSM) remains unclear. PATIENTS AND METHODS We analyzed data from 305,443 women ages 20- to 79-years-old diagnosed with breast cancer between ...

BACKGROUND Auditory laterality is suggested to be characterized by a left hemisphere dominance for the processing of conspecific communication. Nevertheless, there are indications that auditory laterality can also be affected by communicative significance, emotional valence and social recognition. METHODOLOGY/PRINCIPAL FINDINGS In order to gain insight into the effects of caller characteristi...

The scale-eating cichlid fish, Perissodus microlepis, from Lake Tanganyika are a well-known example of an asymmetry dimorphism because the mouth/head is either left-bending or right-bending. However, how strongly its pronounced morphological laterality is affected by genetic and environmental factors remains unclear. Using quantitative assessments of mouth asymmetry, we investigated its origin ...

The quantification of brain asymmetries may provide biomarkers for presurgical localization of language function and can improve our understanding of neural structure-function relationships in health and disease. We propose a new method for studying the asymmetry of the white matter tracts in the entire brain, and we apply it to a preliminary study of normal subjects across the handedness spect...

In the teleost fish Girardinus falcatus eye preferences for inspecting a potential predator is highly heritable and this consented to select lines with opposed laterality. In previous studies individuals from a RD line (rightward turning when facing a dummy predator) and those from a LD line (leftward turning) were subjected to several other laterality tests (most of which, possibly all, were v...

Studies using dichotic listening tasks have reported findings suggestive of alterations of cerebral laterality in schizophrenia and affective disorders. In a review of these findings, an effort was made to take into account four factors: (1) type of dichotic listening task; (2) performance level; (3) clinical state of patients at the time of testing; (4) diagnostic subtype of patients. A conver...