The present study was undertaken to define the effects of left ventricular hypertrophy on postischemic recovery of myocardial performance and high energy phosphate metabolism. Hemodynamics and 3`P-magnetic resonance spectra were monitored simultaneously in the isolated Langendorff-perfused rat heart during 30 minutes of ischemia and 30 minutes of reperfusion. Left ventricular hypertrophy was pr...

Angiotensin-converting enzyme (ACE) inhibitors today are the standard therapy of patients with myocardial infarction and heart failure due to their proven beneficial effects in left ventricular remodeling and left ventricular function. ACE inhibitors have also been demonstrated to lead to regression of left ventricular hypertrophy (LVH). It is believed that the mechanism of action of LVH regres...

Letters to the Editor will be published, if suitable, as space permits. They should not exceed 1000 words (typed double-spaced) in length and may be subject to editing or abridgment. To the Editor: In their prospective study, Gaddam et al 1 have examined the effects of spironolactone on cardiac structure in 34 patients with resistant hypertension who were separated according to their plasma ald...

Left ventricular (LV) function and hypertro:hy, assessed during cardiac catheterization by quantitative biplane angiocardiography, were re'ated to posteatheterization course in 36 patients found to have cardiomyopathy with depressed eject.on fraction (EF). EF ranged from 0.09 to 0.41, LV mass (M) from 99 to 317 g/m2, LV end-diastolic volume (V) from 104 to 347 ml/m2, and ratio of M/V from 0.66 ...

A study of 90 patients with left ventricular hypertrophy revealed a typical configuration of the spatial vectorcardiogram in most of the subjects. Typically the QRS stY-loop was smooth, wide and rounded, inscribed in a counterclockwise direction and placed largely to the left and above the iso-electric point in its frontal plane projection. The left sagittal plane projection of the QRS stY-loop...

BACKGROUND Left ventricular hypertrophy is associated with an increased risk of cardiovascular morbidity and mortality. Previous studies have shown that patients with left ventricular hypertrophy develop electrocardiographic changes and left ventricular dysfunction during acute hypotension, and suggest that the lower end of autoregulation may be shifted upwards. AIM To measure coronary blood ...

lar hypertrophy regresses if athletes decondition; left ventricular systolic function and Doppler measured mitral diastolic filling patterns are usually normal; and, lastly, follow-up studies of elite international standard competitors suggest that they live longer than expected compared to the population mean. However, athletic left ventricular hypertrophy does not only occur in Olympic standa...

patients and methods forty five young female volunteer athletes were included and received different training regimens (endurance-training, strength training and concurrent groups) for a 10 week period as study intervention. standard color doppler echocardiography was performed for assessment of the left ventricular activity. results as a result, 45 athletes ended the study training regimens. m...

BACKGROUND Cardiac structure and function are well-studied in Western countries. However, epidemiological data is still scarce in China. METHODS Our study was conducted in the framework of cardiovascular health examinations for the current and retired employees of a factory and their family members. According to the American Society of Echocardiography recommendations, we performed echocardio...

The pathogenesis of cardiac left ventricular hypertrophy and failure is poorly defined due to the complexity of the disease phenotype. To gain a better understanding of the relationship between gene expression and left ventricular hypertrophy, we employed a quantitative approach to identify genes with expression patterns that correlate in a numerically continuous manner with parameters of cardi...