n engl j med 372;11 nejm.org march 12, 2015 989 shops in the Netherlands, but the new products that are available in the United States are quite dif­ ferent. They are skillfully produced and packaged to closely mimic popular candies and other sweets (see photo). These products can now be purchased legally in four states; retail stores are operating in Colorado and Washington State, and voters r...

Marijuana use has been increasing across the United States due to its legalization as both a medicinal and recreational product. A small number of case reports have described a pathological entity called vanishing lung syndrome (VLS), which is a rare bullous lung disease usually caused by tobacco smoking. Recent case reports have implicated marijuana in the development of VLS. We present a case...

To reduce the risk of infection in highly immunocompromised patients, prophylactic antibacterial, antifungal and antiviral agents are frequently prescribed and patients are routinely advised to reduce their risk of exposure by avoiding soil, plants and cut flowers due to the presence of Aspergillus and other moulds and Nocardia spp. [1,2]. Other recommendations to limit exposures include the av...

AIM To estimate the exposure of Zagreb University medical students to psychoactive substances in 2000 and compare it with data collected in 1989. METHODS Students were surveyed in 2000 (n=775) and 1989 (n=986) by means of a self-reporting questionnaire. The 2000 survey also included 136 non-medical students. General demographic data and data on experience with psychoactive substances were col...

Due to the legalization of marijuana and the increased demand for cannabis and alcohol consumption, research efforts highlighting the biomedical consequences of the use of alcohol and cannabinoids are not only relevant to the substance abuse scientific field, but are also of public health interest. Moreover, an overview of the recent literature about alcohol and cannabinoids neuro-immunomodulat...

Abstract Objective The safety of the United States donor blood supply has been questioned in context recreational marijuana legalization Colorado and other states nationwide. It is unclear whether cannabis use by donors presents a danger to recipients, either through direct toxicity or socioeconomic ramifications. Our objectives are both determine if active metabolite tetrahydrocannabinol (THC)...

As part of the amendment, the state was required to construct legal, regulatory, and tax frameworks that would allow businesses to cultivate, process, and sell marijuana not simply to medical patients—as had been happening in Colorado for over a decade—but to anyone 21 and older. This change came despite existing federal prohibition of marijuana and opposition from the governor, state attorney ...