Gopal, a Hindu male, aged about 42 years, came into Burrisal Dispensary, 10th August, with cataract in both eyes. Was quite blind of right eye for nearly two years, and is almost blind of the left one. Cataract commenced in the right eye about three years ago. An ophthalmoscopic examination was made, but the opacity of the lens was too dense to allow of intraocula inspection. The pupil contract...

s-j syndrome is a rare autosomal recessive disorder of short stature, blepharophimosis, puckerd mouth, myotonia, muscular weakness, pectus carinatum and stiff joints. case report: first case: n.1. a boy aged 7 years. his main abnormalities included puckered lip, blephharophimosis, muscular hypertrophy and weakness, pectus carinatum, short stature, shoulder joint limitation and myopia. myotonic ...

This study evaluated the surgical outcome and complications of phacoemulsification and the implantation of an acryl foldable intraocular lens (IOL) with a squared edge in dogs with cataracts. Thirty-two eyes from 26 dogs were examined. The mean follow up period was 75.9 days ranging from 23 to 226 days. The complications after phacoemulsification were posterior capsular opacity (PCO) around the...

PURPOSE Proliferation of lens epithelial cell (LEC) is main principle for posterior capsular opacity (PCO) following surgery. We investigated whether overexpression of Krüppel-like factor 6 (KLF6) can be employed to increase protein 21 (p21) and protein 27 kinase inhibition protein 1 (p27(kip1)) levels and its effect on proliferation of LEC. METHODS A plasmid containing KLF6 cDNA was used to ...

purpose: to report the outcomes of graft refractive surgery (grs) together with clear-cornea phacoemulsification and intraocular lens (iol) implantation in post-penetrating keratoplasty (pkp) eyes. methods: fourteen eyes of 13 patients who had received pkp underwent simultaneous grs (relaxing incisions with or without counter-quadrant compression sutures) and clear-cornea phacoemulsification wi...

PURPOSE To characterize gene expression patterns between epithelia isolated from cataractous and normal human lenses. METHODS Reverse transcriptase differential display was used to identify differential expression between cataractous and normal epithelia. RT-PCR was used to compare pooled and individual RNA samples. RESULTS One transcript, up-regulated in cataractous as compared to normal e...

The fine structure of the nuclear zone of neonatal mouse lenses can vary considerably according to the fixation used. When normal neonatal mouse lenses are fixed in a commonly used chilled glutaraldehyde solution, the nuclear zone develops a grossly visible opacity, and irregular sized protein granules appear in the subsequent sections. Similar artifacts of aggregated irregular sized protein gr...

Background: The majority of dogs with diabetes mellitus develop blinding mature cataracts through the action of the enzyme aldose reductase producing sorbitol with osmotic action drawing water into the lens thus causing opacification. Here we evaluate the use of OcuGLOTM a formulation including the aldose reductase inhibitor alpha lipoic acid, grapeseed extract, carotenoids, omega-3-fatty acids...

purpose: to evaluate the diagnostic signs, intraoperative complications and postoperative outcomes in children with congenital cataract and pre-existing posterior capsule defect (ppcd). methods: this interventional case series was conducted on 14 eyes of 7 patients who underwent lensectomy-anterior vitrectomy for congenital cataract with ppcd. all children had bilateral cataract. preoperative d...