BACKGROUND Although previous data indicate that the overall incidence of human leptospirosis in the Peruvian Amazon is similar in urban and rural sites, severe leptospirosis has been observed only in the urban context. As a potential explanation for this epidemiological observation, we tested the hypothesis that concentrations of more virulent Leptospira would be higher in urban than in rural e...

Saprophytic leptospires are spirochetes enclosed within the non-pathogenic clade of genus Leptospira, which in turn is subdivided into two subclades S1 and S2. To date, microorganisms included these have been isolated from environment various parts world, believed to no known animal reservoirs. After a case Leptospira interrogans serovar Pomona was notified owner farm Sardinia, all animals (11 ...

Vanaporn Wuthiekanun, Premjit Amornchai, Sayan Langla, Malinee Oyuchua, Nicholas P. J. Day, Direk Limmathurotsakul Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Nuffield Department of Medicine, University of Oxford, Old Road Campus, Headington, Oxford, United Kingdom; Department of Tropical Hygiene, Faculty of Tropical Medic...

Leptospirosis is a zoonotic disease with global distribution that caused by pathogenic spirochetes of the genus Leptospira. Accurate diagnosis for differentiation of leptospirosis from other pyrogenic infections prevailing in the same locality and is imperative for proper treatment. Therefore a molecular diagnostic test with high specificity and sensitivity such as PCR is essential. Gene encodi...

Leptospirosis is a common disease of livestock, pet many countries for cattle, dogs and swine but vaccination may animals and wildlife throughout the world. Sporadic cases and prove only partially effective due to generation of serovar outbreaks of the disease have been reported from USA, U.K, specific immunity, prevalence of several Leptospira serovars Australia, New Zealand, USSR and countrie...

The motility and chemotaxis systems are critical for the virulence of leptospires. In this study, the phylogenetic profiles method was used to predict the interaction of chemotaxis proteins. It was shown that CheW1 links to CheA1, CheY, CheB and CheW2; CheW3 links to CheA2, MCP (LA2426), CheB3 and CheD1; and CheW2 links only to CheW1. The similarity analysis demonstrated that CheW2 of Leptospir...

background: leptospirosis has been recognized as an important reemerging infectious disease caused by pathogenic leptospira spp. a major challenge of this disease is the application of a basic research to improve diagnostic method. outer membrane proteins of leptospira are potential candidates that could be useful in diagnosis. among them the lipl41 is an immunogenic protein which is present on...

This research aims at studying sero infection of leptospira interrogans in farms of Sarab. For this purpose, 200 serum samples were randomly collected. Six kinds of alive leptospira antigens, ballum, canicola, grippotyphosa, icterohaemorrhagia, hardjo,Pomona were isolated using MAT test. The results obtained from this test demonstrated that 23% of animals sera were serologically positive for di...

The data presented in this article are related to the research article entitled "Comparison between Generalized Linear Modelling and Additive Bayesian Network; Identification of Factors associated with the Incidence of Antibodies against Leptospira interrogans sv Pomona in Meat Workers in New Zealand" (Pittavino et al., 2017) [5]. A prospective cohort study was conducted in four sheep slaughter...

Observations of colonial growth of Leptospira interrogans serovar pomona, BJ, on soft-agar (1% agar) plates revealed the presence of both surface and subsurface colonies. The organisms from both types of colonies appeared to be similar in motility, morphology, antigenic composition, and pathogenicity. Passage in vivo tended to produce a higher incidence of surface colonies, whereas passage in v...