Artificially regulating gene expression is an important step in developing new treatment for system-level disease such as cancer. In this paper, we propose a method to regulate gene expression based on sampled-data measurements of gene products concentrations. Inherent noisy behaviour of Gene regulatory networks are modeled with stochastic nonlinear differential equation. To synthesize feed...

Proline dehydrogenase (ProDH; 1.5.99.8) belongs to superfamily of amino acid dehydrogenase, which plays a significant role in the metabolic pathway from proline to glutamate. The goal of this research was gene cloning and characterization of ProDH enzyme from Pseudomonas fluorescens pf-5 strain. The gene encoding ProDH was isolated by means of PCR amplification and cloned in an IPTG inducible T...

This thesis describes the problem of facial expression recognition in the field of computer vision. Firstly, the psychological background of a problem is presented. Then, the idea of facial expression recognition system (FERS) is outlined and the requirements of such system are specified. The FER system consists of 3 stages: face detection, feature extraction and expression recognition. Methods...

We address the batch arrival  systems with finite capacity under partial batch acceptance strategy where service times or rates oscillate between two forms according to the evolution of the number of customers in the system. Applying the theory of Markov regenerative processes and resorting to Markov chain embedding, we present a new algorithm for computing limit distributions of the number cus...

chronic exposure to lead (pb) affects neural functions in central nervous system (cns) particularly the learning and memory. on the other hand, alteration of calcium level in the cns results in activation of nos. it has been shown that lead enters the neurons through calcium channels and displaces ca2+ from calcium binding proteins such as calmodulin and troponin c thereby affecting calcium-med...

Background: Zinc (Zn) as an important trace element is essential for testicular development and spermatogenesis. Molecular mechanism of Zn action in the reproductive system may be related to metal binding low-molecular weight proteins, metallothioneins (MT). Our objective was to determine the effect of Zn on two important isoforms of MT, MT1M and MT1G genes expression on testicular sertoli cell...