A fundamental step in cellular defense mechanisms is the recognition of "danger signals" made of conserved pathogen associated molecular patterns (PAMPs) expressed by invading pathogens, by host cell germ line coded pattern recognition receptors (PRRs). In this study, we used RNA-seq and the Kyoto encyclopedia of genes and genomes (KEGG) to identify PRRs together with the network pathway of dif...

recent studies have shown that glucocorticoids may have modulatory effect on anxiety reactions. this effect may occur with opioid system interference. according to that, the purpose of this research is to assess the effect of dexamethasone as glucocorticoid agonist and its interaction with opioidergic system on the anxiety modulatory effect in plus maze model in mice. male white mice with mediu...