We examined the polymorphisms in the PIT1 gene of 103 pigs and compared their frequencies in the maternal and paternal lineages of the Pietrain and Large White breeds, which have undergone divergent selection for over 30 years. DNA samples extracted from the blood of these animals were amplified by PCR and genotyped by RFLP, using the restriction enzyme RsaI. The data were analyzed with the chi...

The emergence of pre-extensively drug-resistant tuberculosis (pre-XDR-TB) is a threat to TB control programs in developing countries such as Zambia. Studies Zambia have applied molecular techniques understand drug-resistance-associated mutations, circulating lineages and transmission patterns multi-drug-resistant (MDR) Mycobacterium tuberculosis. However, none has reported genotypes mutations a...

In Computer Science, Provenance also known as lineage and pedigree describe the source and derivation of data. Data provenance is key to the management of scientific data and has recently been recognized as central to the trust one places in data. This paper focus attention on the importance and difficulty of provenance tracking in practice. We discuss a taxonomy of data provenance characterist...

The predominant view of embryonic development and cell differentiation has been that rigid and even irreversible epigenetic marks are laid down along the path of cell specialization ensuring the proper silencing of unrelated lineage programmes. This model made the prediction that specialized cell types are stable and cannot be redirected into other lineages. Accordingly, early attempts to chang...

Orkin, 1996, for review). Candidature is merited either *Section of Gene Function and Regulation by virtue of their binding to cis-acting regulatory ele-† Leukaemia Research Fund Centre ments of lineage-specific genes or through association Institute of Cancer Research with leukemia-associated chromosomal translocations. Chester Beatty Laboratories While factors identified in this way probably ...