Full-thickness nasal deformities are a reconstructive challenge. Restoration of a reliable internal lining is critical for a successful reconstruction. Septal hinge flaps are the workhorse for internal lining defects. However, these and other intranasal mucosal flaps are sometimes unavailable due to prior harvest or previous oncologic resection. We present the two-stage interpolated subcutaneou...

Historically, external skin is the most obvious tissue deficiency after nasal trauma or skin cancer excision. The loss of underlying support and lining is less apparent and practically speaking has been considered an afterthought in the repair of nasal defects. The importance of lining was initially recognized by Keegan and Gillies. Modern surgeons can effectively employ both traditional techni...

The histologic pattern of OKC is distinct and hence the cyst has potential for more aggressive behaviour than other cysts of the jaws. When inflammation is present within the cyst wall of an OKC, the character of the cyst lining changes from the classical pattern to a non-keratinized stratified squamous lining typical of other inflammatory cysts. This transformation often occurred quite abruptl...

Ali Hendi, MD, has indicated no significant interest with commercial supporters. A n 80-year-old woman underwent surgery to treat primary basal cell carcinoma on the right nasal ala. The tumor measured 0.9 Â 0.4 cm and appeared to involve the nasal lining (Figure 1). Tumor-free margins were obtained after the first stage of Mohs micrographic surgery. A 1.3 Â 0.6-cm defect involving 2 mm of the ...

Obviously, restoring the nasal lining is a great challenge in the reconstruction of nasal defects. Full thickness nasal defects usually require special flaps for reconstructing the nasal lining. Intranasal mucosal flaps, hinge over flaps, perinasal second flaps, folded or second forehead flaps and finally free flaps are examples that can be used for this purpose. Moreover, the case presented in...

Long-term soft denture lining (LTSDL) materials are used to alleviate the trauma associated with wearing complete dentures. Despite their established clinical efficacy, the use of LTSDLs has been limited due to the unfavorable effects of the oral environment on some of their mechanical and performance characteristics. The unresolved issue of LTSDL colonization by Candida albicans is particularl...

The epithelium lining the mouse larynx occupied the transitional zone between the keratinized stratified squamous epithelium lining the oral cavity and the ciliated columnar one continuing to the trachea. The epithelium showed gradations ranging from stratified squamous through stratified cuboidal to ciliated stratified low-columnar type. It is suggested that the epithelium is identical with th...

In this issue of Neuron, Roelfsema and Spekreijse report that macaque V1 neuron responses are correlated with target choice in a task requiring monkeys to attentively trace a line to plan a saccade. These results provide evidence that V1 is actively involved in the interpretation of visual stimuli.

Respiratory tract lining fluids (RTLFs) are a heterogeneous group of substances covering the respiratory tract epithelial cells (RTECs) from nasal mucosa to alveoli. Antioxidant contained in the RTLFs can be expected to provide an initial defense against inhaled environmental toxins. The major antioxidants in RTLF include mucin, uric acid, protein (largely albumin), ascorbic acid, and reduced g...