نتایج جستجو برای: lisdexamfetamine
تعداد نتایج: 296 فیلتر نتایج به سال:
BACKGROUND Attention-deficit/hyperactivity disorder (ADHD) is increasingly recognized as a persistent disorder requiring long-term management. OBJECTIVES Our objective was to evaluate the 2-year safety and efficacy of lisdexamfetamine dimesylate (LDX) in children and adolescents with ADHD. METHODS Participants (aged 6-17 years) with ADHD received open-label, dose-optimized LDX 30, 50, or 70...
Background: Lisdexamfetamine dimesylate (LDX) is a therapeutically inactive amphetamine prodrug. It was developed with the goal of providing an extended duration of effect that is consistent throughout the day, with a reduced potential for abuse, overdose toxicity, and drug tampering. Following ingestion, the pharmacologically active d-amphetamine molecule is gradually released by rate-limited ...
BACKGROUND Psychostimulants are considered first-line pharmacotherapy for youth with attention-deficit/hyperactivity disorder (ADHD), but questions remain regarding the comparative efficacy of amphetamine- and methylphenidate-based agents. OBJECTIVE Our objective was to describe two acute randomized, double-blind, placebo-controlled, head-to-head studies of lisdexamfetamine dimesylate (LDX) a...
Vic Norris1,2, Abdallah Zemirline1,3, Patrick Amar1,4, Pascal Ballet1,3, Eshel Ben Jacob5, Gilles Bernot1, Guillaume Beslon1,6, Eric Fanchon1, Jean-Louis Giavitto1,7, Nicolas Glade1, Patrick Greussay1, Yohann Grondin1, James A. Foster8, Guillaume Hutzler1, Francois Kepes1, Olivier Michel1,7, Gradimir Misevic1,2, Franck Molina1,9, Jacqueline Signorini1, Pasquale Stano10 and Alain Thierry1,11 1Ep...
BACKGROUND To investigate the effect of lisinopril on cardiac remodeling induced by smoking. MATERIAL/METHODS Rats were allocated into 3 groups: group CON (n=8): control; group CSE (n=8): cigarette smoke exposure; group CSE-LIS (n=8): exposed to tobacco smoke and treated with lisinopril. RESULTS After 2 months, the tail systolic pressure was lower in CSE-LIS (CON=116 +/-27 mm Hg, CSE=126+/-...
S h a a th a n d I s r a e l ’s te a m chief, Maj. Gen. Amnon Shahak, sounded optimistic. Each p re d ic te d a b o u t tw o m o re w eeks of ta lk s . But th e te n dency to delegate upw ard has stalled the talks for months in the past. This w eek’s security talks fo cused on the Palestinian police force and the release of Pales tin ia n s ja ile d in Israe l. Both sides said the police is...
AIMS To detect clonal T cell populations by high resolution polymerase chain reaction (PCR) using fluorescently labelled nucleotides and analysis on an ABI 377 DNA sequencer, and to evaluate this method using low ionic strength single strand conformation polymorphism (LIS-SSCP) analysis. METHODS DNA samples from 11 patients diagnosed with a T cell disease and 15 with no known T cell disorder ...
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