pregnancies. Pregnancy encompasses a wide variety of physiological changes with increased, decreased or unchanged parameters. Liver function abnormality can represent a physiological change, but elevations of transaminase, bilirubin, and prothrombin time almost always indicate a pathologic state. The major physiologic changes in pregnancy, that peak in second trimester and plateau at delivery, ...

One hundred and four adult patients with cystic fibrosis were evaluated for the presence of liver disease as defined by abnormal liver function tests of six months' duration, histological evidence of fibrosis or cirrhosis, or the presence of portal hypertension, or both. Twenty patients fulfilled these criteria and were evaluated further for the presence of biliary tract abnormalities with bili...

Alterations in the haemostatic system were characterized in cats with different naturally occurring liver diseases. The study looked at 44 healthy cats and 45 cats with different liver diseases confirmed histologically or cytologically (neoplasia, n=9; inflammation, n=12; hepatic lipidosis, n=13; other degenerative liver diseases, n=11). The following parameters were evaluated: platelet count; ...

skeletal abnormalities are most often used to describe defects in the arms or legs that are associated with genes or chromosomes, or that occur due to an event that happens during pregnancy. spider lamb syndrome (sls) is a congenital disorder in sheep breeding that is recognized by some deformities in skeletal system especially in the limbs.a dead day-old cross-breed white lamb with deformed li...

BACKGROUND Karyomegalic nephropathy, first identified in 1974, represents an increasingly recognized, but perhaps underdiagnosed condition associated with interstitial nephritis. It undoubtedly leads to end-stage renal disease requiring renal support. METHODS AND RESULTS We present a series of six cases of karyomegalic nephropathy. The age at diagnosis was 9-51 years, median 33 years. Impaire...

BACKGROUND The vasopressin type 2 receptor antagonist tolvaptan (TLV) has recently become available for treating congestion. However, there is no evidence confirming the efficacy of TLV for patients with volume overload after cardiac surgery. Here, we retrospectively studied the efficacy of TLV in patients with volume overload after cardiac surgery. METHODS We enrolled a total of 39 patients ...

Background No study to date has focused on the changes in laboratory test results and related risk factors in patients with psoriasis treated with prolonged Cyclosporine A (CsA) therapy. Objective The objective of this study was to investigate the changes of laboratory values and related risk factors in patients with psoriasis treated with CsA in a real-world setting. Methods Records of pat...

CONGENITAL hepatic fibrosis is an uncommon cause of portal hypertension and usually presents as alimentary bleeding in childhood or adolescence. The occurrence in more than one member of a family has been described (Kerr et al., 1961; Campbell et al., 1958). This report concerns four members of one family who have presented with clinical features attributable to congenital hepatic fibrosis. Pat...