Four cases of cauda equina syndrome occurring after continuous spinal anesthesia are reported. In all four cases, there was evidence of a focal sensory block and, to achieve adequate analgesia, a dose of local anesthetic was given that was greater than that usually administered with a single-injection technique. We postulate that the combination of maldistribution and a relatively high dose of ...

PULPECTOMY – Treatment Considerations Anesthesia It is essential to eliminate any sensation from the tooth being treated prior to endodontic therapy. While it is true that some necrotic teeth can be treated without anesthesia, placement of rubber dam clamps and instrumentation beyond the apex (patency filing) normally make the use of local anesthetic desirable. This is typically achieved throug...

BACKGROUND Achieving adequate control of postsurgical pain remains a challenge in patients undergoing abdominal surgery. Transversus abdominis plane (TAP) infiltration has been shown to provide postsurgical analgesia following lower abdominal surgery. We assessed the safety and efficacy of a prolonged-release liposomal formulation of the local anesthetic bupivacaine administered via infiltratio...

To measure the depth of the local anesthetic binding site within the neuronal membrane, biotin-containing polyethylene glycols having zero, three, and six ethylene glycol subunits were added to the p-amino termini of tetracaine and procaine, thereby interposing a pharmacologically inert "spacer" molecule between the local anesthetic and the biotin moiety. These biotinyl-local anesthetic derivat...

background and aims. current infiltration techniques for achieving anesthesia in dental procedures are not applicable in posterior mandibular region because of its dense cortical bone. the aim of this study was to evaluate the efficacy of a specific infiltration anesthesia in posterior mandibular teeth instead of inferior alveolar nerve block for restorative procedures. materials and methods. c...

Background. The general toxic effects of local anesthetics on vital organs are the most severe side regional blockades. purpose was to study effectiveness and safety combined solutions in brachial plexus block. Materials methods. Forty-nine patients were divided into 2 groups. first group (controls) consisted 24 individuals who received a solution 0.5% bupivacaine 36 ml (180 mg) with adrenaline...