نتایج جستجو برای: long noncoding rna

تعداد نتایج: 1007963  

Journal: :Cancer research 2015
Brian D Adams Eleni Anastasiadou Manel Esteller Lin He Frank J Slack

This report summarizes information presented at the 2015 Keystone Symposium on "MicroRNAs and Noncoding RNAs in Cancer." Nearly two decades after the discovery of the first miRNA, the role of noncoding RNAs in developmental processes and the mechanisms behind their dysregulation in cancer has been steadily elucidated. Excitingly, miRNAs have begun making their way into the clinic to combat dise...

Journal: :Journal of Cell Science 2021

ABSTRACT The heat-shock response is critical for the survival of all organisms. Metastasis-associated long adenocarcinoma transcript 1 (MALAT1) a noncoding RNA localized in nuclear speckles, but its physiological role remains elusive. Here, we show that heat shock induces translocation MALAT1 to distinct body named shock-inducible RNA-containing (HiNoCo) mammalian cells. MALAT1-knockout A549 ce...

Journal: :Proceedings of the National Academy of Sciences 2017

Journal: :American Journal of Respiratory Cell and Molecular Biology 2020

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