Macrophages play a pivotal role in innate immune responses to pathogens via toll-like receptors. We previously demonstrated that aryl hydrocarbon receptor (Ahr) in combination with signal transducer and activator of transcription 1 (Stat1) negatively regulates pro-inflammatory cytokine production by inhibiting nuclear factor-κB activation in macrophages after LPS stimulation. Here, we show that...

acetaminophen and tramadol ............... 22 ADIPOKINETIX ................ 21 ADRENALIN .................... 21 ALPHADRINE .................. 21 amitriptyline ..................... 22 ANAFRANIL..................... 22 cefdinir ............................ 24 cefditoren ......................... 23 cefpodoxime .................... 24 CEFTIN ............................ 24 cefuroxime ..............

patients with allergic rhinitis (ar) show increased production of the th2-related cytokines. almost always, intranasal corticosteroid (inc) and antihistamine are used as routine therapy of ar. this study was performed to determine the in vitro secretion of cytokines profiles of pbmcs in patients with ar sensitive to chenopodium album (ch.a) pollens before and after treatment with inc (fluticaso...

Histamine (one of the key mediators released from mast cells and basophils), plays a major role in the pathophysiology of allergic diseases, including rhinitis, urticaria, asthma and anaphylaxis. Histamine exerts its effects through its interaction with one of four distinct receptors (H1, H2, H3, H4). In allergic disease, it is the H1 antihistamines which are of primary benefit, although H2 ant...