The article entitled "Evaluation of the Analytical Performance of the Coulometry-Based Optium Omega Blood Glucose Meter", by Solnica and colleagues in this issue of Journal of Diabetes Science and Technology demonstrates that the Optium Omega blood glucose meter meets the analytical requirements for glucose meter performance and it is stated that the results are clinically useful. The authors s...

We examined the analytical performance of eight compact systems for measuring total cholesterol: AccuMeter, Cobas Ready, Discovery f2, DT60, L-D-X, Reflotron, QCA, and Vision. We determined average bias at two decision levels, the mean absolute bias, and the percentage of results differing from the comparison method results by > 8.9% allowable total error limit for multiple reagent lots. Averag...

OBJECTIVE Overall, 2%-5% of patients with multiple sclerosis (MS) experienced the first episode of disease before the age 18 years old. Since the age of onset among children is not similar to that in general population, clinicians often fail to early diagnose the disease. This study aimed to determine the epidemiological and clinical patterns of MS among Iranian children. MATERIALS & METHODS ...

Coordinated input from a variety of health and social care professionals into medical education helps students to become strong, effective, successful and competent future practitioners able to function within the multi-disciplinary environment which characterizes modern medicine. This paper presents a new model of teaching developed within the context of the Phase 1 Medicine Programme at Durha...

This paper considers the multi-item dynamic lot size model where joint business volume discount is applied for all items purchased whenever the total dollar value of an order reaches a certain level. Multi-item discounts are prevalent in practical applications, yet the literature has only considered limited instances of single-item models. We establish the mathematical formulation and design an...

This paper examines the optimal production lot size decisions for clinical trial supply chains. One unique aspect of clinical trial supply chains is the risk of failure, meaning that the investigational drug is proven unsafe or ineffective during human testing and the trial is halted. Upon failure, any unused inventory is essentially wasted and needs to be destroyed. To avoid waste, manufacture...

This paper introduces the Special Issue of Neuropsychological Rehabilitation on Single Case Experimental Design (SCED) methodology. SCED studies have a long history of use in evaluating behavioural and psychological interventions, but in recent years there has been a resurgence of interest in SCED methodology, driven in part by the development of standards for conducting and reporting SCED stud...

In this paper, we use integer programming (IP) to compute minimal forecast horizons for the classical dynamic lot-sizing problem (DLS). As a solution approach for computing forecast horizons, integer programming has been largely ignored by the research community. It is our belief that the modelling and structural advantages of the IP approach coupled with the recent significant developments in ...

the vehicle routing problem with simultaneous pickup and delivery (vrpspd) is a well-known combinatorial optimization problem which addresses provided service to a set of customers using a homogeneous fleet of capacitated vehicles. the objective is to minimize the distance traveled. the vrpspd is an np-hard combinatorial optimization problem. therefore, practical large-scale instances of vrpspd...

in the recent decade, special attention is paid to reverse logistic due to economic benefits of recovery and recycling of used products as well as environmental legislation and social concerns. on the other hand، many researches claim that separately and sequential planning of forward and reverse logistic causes sub-optimality. effective transport activities are also one of the most important c...