UNLABELLED While the detrimental effects of cranial radiotherapy on the developing brain are well known, the effects on cognitive performance of low doses of ionizing radiation is less studied. We performed a population-based cohort study to determine whether low doses of ionizing radiation to the brain in infancy affects cognitive function later in life. Further we hypothesized that the dose t...

Background Although the effects of high dose radiation on human cells and tissues are relatively well defined, there is no consensus regarding the effects of low and very low radiation doses on the organism. Ionizing radiation has been shown to induce gene mutations and chromosome aberrations which are known to be involved in the process of carcinogenesis. The induction of secondary cancers is ...

Background: The International Commission on Radiological Protection (ICRP) has attributed the same relative risk for X and gamma radiations of all energies. Several studies have proven that the biological effect of low energy photon is more than that of higher ones. The assessment of risks is important due to the wide use of low energy X-rays for mammography screening and other diagnostic appli...

introduction exposure to chronic levels of ionizing radiation could be detrimental to health even at very low doses. calabar free trade zone (cftz) was established to promote export business in nigeria and it is yet to produce exposure data of the zone. materials and methods the zone was divided into three categories depending on the type of business. category a had facilities with manufacturin...

Cosmic rays are known to cause biological effects directly and through ionizing radiation produced by their secondaries. These effects have been detected in airline crews and other specific cases where members of the population are exposed to above average secondary fluxes. Recent work has found a correlation between solar particle events and congenital malformations. In this work we use the re...

We previously demonstrated that exposure of certain human tumor cells to very low chronic doses of ionizing radiation led to their enhanced survival following exposure to subsequent high doses of radiation. Survival enhancement due to these adaptive survival responses (ASRs) ranged from 1.5-fold to 2.2-fold in many human tumor cells. Furthermore, we showed that ASRs result from altered G1 check...

BACKGROUND Although genes involved in apoptosis pathways and DNA repair pathways are both essential for maintaining genomic integrity, genetic variants in DNA repair have been thought to increase susceptibility to radiation carcinogenesis, but similar hypotheses have not generally been raised about apoptosis genes. For this reason, potential modification of the relationship between ionizing rad...