Chronic obstructive pulmonary disease (COPD) is characterized by poorly reversible airflow limitation. The pathological hallmarks of COPD are inflammation of the peripheral airways and destruction of lung parenchyma or emphysema. The functional consequences of these abnormalities are expiratory airflow limitation and dynamic hyperinflation, which then increase the elastic load of the respirator...

Static lung volume measurements allow objective assessment of total lung capacity (TLC), functional residual capacity (FRC) and residual volume, and assist in the diagnosis and management of lung disease [1, 2]. The use of gas dilution techniques, such as multiple-breath nitrogen washout (MBNW), require minimal patient cooperation and allow FRC to be determined in those individuals unable to co...

inspiratory capacity is often decreased in PAH, and that this is associated with a decreased aerobic exercise capacity and a shorter life expectancy. Inspiratory capacity is the difference between total lung capacity and functional residual capacity, and as such increases in the presence of expiratory airflow limitation or dynamic hyperinflation. The authors measured in 50 patients with PAH an ...

Halocnemum strobilaceum is a halophyte present in the humid and arid bioclimatic regions of Egypt. The current study aimed at UPLC/PDA/ESI-MSn qualitative chemical profiling of the phytoconstituents underlining both antioxidant and cytotoxic activities of the bio-active fraction in comparison with the other fractions. It resulted in detection of several related compounds to prenylated flavonol ...