Computer system batch schedulers typically require information from the user upon job submission, including a runtime estimate. Inaccuracy of these runtime estimates, relative to the actual runtime of the job, has been well documented and is a perennial problem mentioned in the job scheduling literature. Typically users provide these estimates under circumstances where their job will be killed ...

Vinculin, a mechanotransducer associated with adherens junctions (AJ) and focal adhesions (FA), plays central role in force transmission through cell-cell cell-substratum contacts. Previously, we generated mice conditional knockout (KO) of vinculin the skin, which results loss bulge stem cell (BuSC) quiescence, promotes continual cycling hair follicles. Surprisingly, found that AJs KO cells are...

As of 2014, cardiovascular disease (CVD) was listed as the underlying cause for 1 of every 3 deaths in the United States. Many forms of CVD have a strong genetic component, and the number of causal genes elucidated greatly depends on the type of CVD under study. Understanding the molecular basis of CVD can guide medical decisions of the practitioner, patient, and family members. Currently, gene...

The nuclear envelope segregates the nucleoplasm from the cytoplasm and is a key feature of eukaryotic cells. Nuclear envelope architecture is comprised of two concentric membrane shells which fuse at multiple sites and yet maintain a uniform separation of 30-50 nm over the rest of the membrane. Studies have revealed the roles for numerous nuclear proteins in forming and maintaining the architec...

Many induction programs use decision trees both as the basis for their search, and as a representation of their classifier solution. In this paper we propose a new structure, called SE-tree, as a more general alternative. Comments University of Pennsylvania Department of Computer and Information Science Technical Report No. MSCIS-93-42. This technical report is available at ScholarlyCommons: ht...