PURPOSE We tested the hypothesis that the macular ganglion cell layer (GCL) thickness demonstrates a stronger structure-function (SF) relationship and extends the useful range of macular measurements compared with combined macular inner layer or full thickness. METHODS Ninety-eight glaucomatous eyes and eight normal eyes with macular spectral domain optical coherence tomography (SD-OCT) volum...

BACKGROUND Inner (area adjacent to the fovea) and outer regions of the macula differ with respect to relative thicknesses of the ganglion cell layer (neurons) vs retinal nerve fiber layer (RNFL; axons). OBJECTIVE To determine how inner vs outer macular volumes relate to peripapillary RNFL thickness and visual function in multiple sclerosis (MS) and to examine how these patterns differ among e...

purpose : the aim of this study is to measure the endogenous cortisol levels in the patients with central serous chorioretinopathy (cscr) and also, evaluate the short-term effect of oral ketoconazole in the treatment of both acute and chronic cscr. methods : in this prospective interventional case series 12 patients with acute cscr and 7 patients with chronic cscr (including one patient with bi...

INTRODUCTION Pseudoxanthoma elasticum (PXE) typically involves elastic fibers in blood vessels and Bruch membrane. Our purpose was to analyze retinal and choroidal macular thickness in patients with angioid streaks due PXE compared with a control group. METHODS Best-corrected visual acuity (BCVA), axial length (AL), and macular swept-source optical coherence tomography were obtained. Automate...

background: cystoid macular edema (cme) is one of the most common and sight threatening complications of uveitis. intravitreal injection of corticosteroids and anti-vegf antibody are two routine options for treatment. objective: to compare the effects of intravitreal injections of bevacizumab and triamcinolone acetonide for the treatment of persistent macular edema in non-infectious uveitis. me...

PURPOSE To assess the test-retest variability of central and sectorial macular thickness measurements obtained by Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA) in neovascular age-related macular degeneration (nAMD). METHODS Macular thickness measurements of nine standard ETDRS subfields were obtained and analyzed. The repeatability of macular thickness measurements by Cirrus HD-OCT was asses...

OBJECTIVE To present the clinical spectrum of lamellar macular defects and describe the different subtypes based on their optical coherence tomography (OCT) configuration and visual prognosis. METHODS The retrospective observational case series reviewed OCT scans of 92 eyes with lamellar macular defects. Lamellar macular defects were categorised into subtypes of macular pseudohole (MPH), lame...

BACKGROUND Diabetic macular edema (DME) is one of the manifestations of diabetic retinopathy leading to loss of central vision and visual acuity. It manifests itself with swelling around the central part of the retina, the area responsible for sharp vision. Current treatment includes laser therapy and intravitreal steroids with preventative measures including diabetes control. No one treatment ...

This study was performed to evaluate optic disc appearance, retinal nerve fiber layer (RNFL) thickness, and macular thickness in normal, ocular hypertensive (OHT) and glaucomatous eyes using optical coherence tomography (OCT) 3000. One hundred fifty-eight eyes of 167 consecutive subjects were enrolled: 60 normal, 53 OHT, and 54 glaucomatous. OCT topographic parameters of cup diameter, cup area,...

Introduction: Primary open-angle glaucoma is a silent predator of sight, killing retinal ganglion cells (RGCs), and leads to characteristic optic nerve head (ONH) changes visual field (VF) defects. The conventional methods diagnosis include clinical examination perimetry. However, by these at the time diagnosis, substantial loss RGCs has already occurred. Spectral domain optical coherence tomog...