Oral mesalazine represents a crucial front-line agent for the treatment of active ulcerative colitis (UC) and the maintenance of remission. Clinical aspects of mesalazine therapy are guided by robust evidence-based guidelines, although there is a relative paucity of guidance examining the specific administrative and professional issues faced by inflammatory bowel disease (IBD) nurses. As IBD nu...

Condition-based maintenance (CBM) is a maintenance strategy that collects and assesses real-time information, and recommends maintenance decisions based on the current condition of the system. In recent decades, research on CBM has been rapidly growing due to the rapid development of computerbased monitoring technologies. Research studies have proven that CBM, if planned properly, can be effect...

This paper presents a generic modeling framework to simultaneously decide about production quantities and maintenance operations for a capacitated resource facing a dynamic demand for different types of products. As the resource needs to be setup for each specific type of product, a lot-sizing problem occurs. In addition it is assumed that production causes intensive wear and tear. For this rea...

Most existing condition based maintenance (CBM) work reported in the literature only focuses on determining the optimal CBM policy for single units. Replacement and other maintenance decisions are made independently for each component, based on the component’s age, condition monitoring data and the CBM policy. In this paper, a CBM optimization method is proposed for multi-component systems, whe...

Mapping the technical and financial effectiveness of a production is crucial for making cost-effective maintenance decisions. But, a successful mapping cannot be achieved without a well-structured database including all relevant data required for this task. The problem addressed in this paper is how to identify the relevant variables and performance measures that should be monitored for achievi...

The primary objective of the project was the development of criteria to define the end-of– life condition of pavements. These criteria could then be used in pavement performance modelling to obtain a more robust measure of remaining life. Another objective was the generation of a new model for maintenance costs. This could then be combined with the existing models for roughness and rutting to d...

On maintenance optimization for offshore wind farms FRANÇOIS BESNARD Abstract The maintenance cost is known to be an important part of the levelized cost of energy generated by wind parks. Operational costs can be significantly reduced by optimizing decisions for maintenance strategies, maintenance support organization and maintenance planning. This is especially important for offshore wind pow...