Background: Active malaria detection is required, for efficient identification of cases or clusters to eliminate malaria. Objective this study was explore prevalence asymptomatic parasite carriage and active among rural residents Anger Gute area. Methods: Community based cross-sectional survey done 413 individuals two villages area from 14 29, August 2020. Malaria infection screened using RDT f...

Aim: The aim of the present study was to characterize role ABO/Rhesus blood group antigen polymorphism in malaria among adults Bayelsa State, Niger Delta, Nigeria. pattern distribution area also assessed.
 Materials and Methods: Two hundred six (91 males 115 females) were randomly selected for they examined presence parasite infection illness as well type using real time PCR-high resolutio...

Higher plants and several photosynthetic algae contain the plastidic 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate pathway (DOXP/MEP pathway) for isoprenoid biosynthesis. The first four enzymes and their genes are known of this novel pathway. All of the ca. 10 enzymes of this isoprenoid pathway are potential targets for new classes of herbicides. Since the DOXP/MEP pathway ...

ahaptoglobinemia is a common phenomenon in tropical countries,where it is probably due to malaria-induced haemolysis. previous studies have suggested that ahaptoglobinemia is more useful than the other parasite detection indexes to estimate the endemicity of malaria. the present study shows the relationship between malaria and haptoglobin, as a genetic marker in balouch population of sistan & b...

Plasmodium infections result in clinical presentations that range from asymptomatic to severe malaria, resulting in ∼1 million deaths annually. Despite this toll on humanity, the factors that determine disease severity remain poorly understood. Here, we show that the gut microbiota of mice influences the pathogenesis of malaria. Genetically similar mice from different commercial vendors, which ...

Quantification of parasite density is an important component in the diagnosis of malaria infection. The accuracy of this estimation varies according to the method used. The aim of this study was to assess the agreement between the parasite density values obtained with the assumed value of 8,000 cells/μL and the automated WBC count. Moreover, the same comparative analysis was carried out for oth...

The duration of infection is fundamental to the epidemiological behaviour of any infectious disease, but remains one of the most poorly understood aspects of malaria. In endemic areas, the malaria parasite Plasmodium falciparum can cause both acute, severe infections and asymptomatic, chronic infections through its interaction with the host immune system. Frequent superinfection and massive par...

Ever increasing drug resistance by Plasmodium falciparum, the most virulent of human malaria parasites, is creating new challenges in malaria chemotherapy. The entire genome sequences of P. falciparum and the rodent malaria parasite, P. yoelii yoelii are now available. Extensive genome sequence data from other Plasmodium species including another important human malaria parasite, P. vivax are a...

Despite recent progress in reducing deaths attributable to malaria, it continues to claim approximately 500,000 lives per year and is associated with approximately 200 million infections. New tools, including safe and effective vaccines, are needed to ensure that the gains of the last 15 years are leveraged toward achieving the ultimate goal of malaria parasite eradication. In 2015, the Europea...

Nitric oxide (NO) is thought to be an important mediator and critical signaling molecule for malaria immunopathology; it is also a target for therapy and for vaccine. Inducible nitric oxide synthase (iNOS) is synthesized by a number of cell types under inflammatory conditions. The most relevant known triggers for its expression are endotoxins and cytokines. To date, there have been conflicting ...